Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR031203-14
Application #
2078764
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1983-04-01
Project End
1997-08-31
Budget Start
1995-09-01
Budget End
1997-08-31
Support Year
14
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Kono, Dwight H; Baccala, Roberto; Theofilopoulos, Argyrios N (2013) TLRs and interferons: a central paradigm in autoimmunity. Curr Opin Immunol 25:720-7
Baccala, Roberto; Gonzalez-Quintial, Rosana; Blasius, Amanda L et al. (2013) Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus. Proc Natl Acad Sci U S A 110:2940-5
Lawson, Brian R; Eleftheriadis, Theodoros; Tardif, Virginie et al. (2012) Transmethylation in immunity and autoimmunity. Clin Immunol 143:8-21
Baccala, Roberto; Gonzalez-Quintial, Rosana; Schreiber, Robert D et al. (2012) Anti-IFN-ýý/ýý receptor antibody treatment ameliorates disease in lupus-predisposed mice. J Immunol 189:5976-84
Gonzalez-Quintial, Rosana; Lawson, Brian R; Scatizzi, John C et al. (2011) Systemic autoimmunity and lymphoproliferation are associated with excess IL-7 and inhibited by IL-7R? blockade. PLoS One 6:e27528
Theofilopoulos, Argyrios N; Gonzalez-Quintial, Rosana; Lawson, Brian R et al. (2010) Sensors of the innate immune system: their link to rheumatic diseases. Nat Rev Rheumatol 6:146-56
Berger, Michael; Krebs, Philippe; Crozat, Karine et al. (2010) An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence. Nat Immunol 11:335-43
Aït-Azzouzene, Djemel; Kono, Dwight H; Gonzalez-Quintial, Rosana et al. (2010) Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice. J Immunol 185:1015-27
Wickramarachchi, Dilki C; Theofilopoulos, Argyrios N; Kono, Dwight H (2010) Immune pathology associated with altered actin cytoskeleton regulation. Autoimmunity 43:64-75
Shvets, Anna; Chakrabarti, Rabindranath; Gonzalez-Quintial, Rosana et al. (2009) Impaired negative regulation of homeostatically proliferating T cells. Blood 113:622-5

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