Abstract

This project continues our study of the compliant behavior at the human elbow, ankle and wrist produced by muscle and neural control mechanisms. We will apply controlled changes or torque to resisting or relaxed limbs and measure the resultant motion and electromyographic responses. We are interested in more completely describing the behavior of the limb under such perturbations in terms of its visco-elastic and plastic behaviors. By carefully studying the temporal variation in these behaviors, we hope to separate purely muscular mechanism from more variable neural control mechanisms. The parametric descriptions that are measured experimentally will be used to build non-linear computer models of the limb and the muscles. Such models have a dual purpose. They are directly useful in biomechanical studies such as predicting head motion following sudden impacts to the body or head. In our own lab, the model will be used to help interpret the electromyographic controlling signals that are observed in muscles during voluntary movements.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR033189-08
Application #
3156528
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1983-12-01
Project End
1993-01-31
Budget Start
1991-02-15
Budget End
1992-01-31
Support Year
8
Fiscal Year
1991
Total Cost
Indirect Cost

  Institution

Name
Rush University Medical Center
Department
Type
DUNS #
City
Chicago
State
IL
Country
United States
Zip Code
60612

  Publications

Vaillancourt, David E; Prodoehl, Janey; Sturman, Molly M et al. (2006) Effects of deep brain stimulation and medication on strength, bradykinesia, and electromyographic patterns of the ankle joint in Parkinson's disease. Mov Disord 21:50-8
Prodoehl, Janey; MacKinnon, Colum D; Comella, Cynthia L et al. (2006) Rate of force production and relaxation is impaired in patients with focal hand dystonia. Parkinsonism Relat Disord 12:363-71
Prodoehl, Janey; MacKinnon, Colum D; Comella, Cynthia L et al. (2006) Strength deficits in primary focal hand dystonia. Mov Disord 21:18-27
Shapiro, Mark B; Prodoehl, Janey; Corcos, Daniel M et al. (2005) Muscle activation is different when the same muscle acts as an agonist or an antagonist during voluntary movement. J Mot Behav 37:135-45
Robichaud, Julie A; Pfann, Kerstin D; Vaillancourt, David E et al. (2005) Force control and disease severity in Parkinson's disease. Mov Disord 20:441-50
Thomas, James S; Corcos, Daniel M; Hasan, Ziaul (2005) Kinematic and kinetic constraints on arm, trunk, and leg segments in target-reaching movements. J Neurophysiol 93:352-64
Pfann, K D; Robichaud, J A; Gottlieb, G L et al. (2004) Muscle activation patterns in point-to-point and reversal movements in healthy, older subjects and in subjects with Parkinson's disease. Exp Brain Res 157:67-78
Vaillancourt, David E; Mayka, Mary A; Thulborn, Keith R et al. (2004) Subthalamic nucleus and internal globus pallidus scale with the rate of change of force production in humans. Neuroimage 23:175-86
Vaillancourt, David E; Prodoehl, Janey; Verhagen Metman, Leo et al. (2004) Effects of deep brain stimulation and medication on bradykinesia and muscle activation in Parkinson's disease. Brain 127:491-504
Robichaud, Julie A; Pfann, Kerstin D; Comella, Cynthia L et al. (2004) Greater impairment of extension movements as compared to flexion movements in Parkinson's disease. Exp Brain Res 156:240-54

Showing the most recent 10 out of 69 publications