Chronic pain is a significant problem for many osteoarthritis patients. The ultimate goal of this research is to develop better ways to evaluate and treat this pain. Our preliminary research revealed that pain coping strategies can be reliably assessed using a questionnaire developed in our laboratory. A Pain Control and Rational Thinking factor identified through factor analysis of questionnnaire responses explain a significant proportion of variance in pain, physical disability, and psychological disability. This factor was a much stronger predictor of pain and functional impairment than x-ray ratings of disease severity, obesity status, or age. The proposed study examines whether a cognitive- behavioral intervention designed to improve patients' pain coping skills and increase their scores on the Pain Control and Rational Thinking factor will improve patients' pain and functional status. One hundred and fifty patients having chronic knee pain and radiographic evidence of osteoarthritis of the knees will be randomly assigned to three conditions: pain coping skill training, arthritis education, or standard care. Subjects in the pain coping skills condition will attend 10 weekly group sessions training them to recognize and reduce irrational cognitions and use attention diversion and changes in activity patterns to control and decrease pain. Arthritis education subjects will attend 10 weekly group sessions providing them with detailed information on osteoarthritis. Standard care subjects will receive the standard care provided to osteoarthritic knee pain patients. Data will be analyzed in order to: 1) compare the efficacy of pain coping skills training to arthritis education and standard care control on both a short-term (10 week) and long-term (6 months) basis, and 2) analyze the relationship of changes in pain coping strategies to improvements in pain and function. The longterm benefit of this research is that it may provide osteoarthritis patients with more effective means of coping with a chronic and often progressive disease. If the cognitive-behavioral intervention is effective, it could be applied in future studies to osteoarthritis patients having pain in other major joints such as the hip. Programmatic research also could be carried out to identify the elements of the intervention that contribute most to treatment effects. By isolating active ingredients, one could streamline treatment, making it more cost effective and thus more readily available to the large population of individuals having osteoarthritic pain.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
2R01AR035270-03
Application #
3157126
Study Section
Behavioral Medicine Study Section (BEM)
Project Start
1985-05-01
Project End
1990-04-30
Budget Start
1987-05-01
Budget End
1988-04-30
Support Year
3
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Duke University
Department
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Keefe, Francis J; Blumenthal, James; Baucom, Donald et al. (2004) Effects of spouse-assisted coping skills training and exercise training in patients with osteoarthritic knee pain: a randomized controlled study. Pain 110:539-49
Jensen, Mark P; Keefe, Francis J; Lefebvre, John C et al. (2003) One- and two-item measures of pain beliefs and coping strategies. Pain 104:453-69
Keefe, F J; Lefebvre, J C; Kerns, R D et al. (2000) Understanding the adoption of arthritis self-management: stages of change profiles among arthritis patients. Pain 87:303-13
Keefe, F J; Lefebvre, J C; Egert, J R et al. (2000) The relationship of gender to pain, pain behavior, and disability in osteoarthritis patients: the role of catastrophizing. Pain 87:325-34
Weiner, D; Peterson, B; Ladd, K et al. (1999) Pain in nursing home residents: an exploration of prevalence, staff perspectives, and practical aspects of measurement. Clin J Pain 15:92-101
Affleck, G; Tennen, H; Keefe, F J et al. (1999) Everyday life with osteoarthritis or rheumatoid arthritis: independent effects of disease and gender on daily pain, mood, and coping. Pain 83:601-9
Weiner, D; Peterson, B; Keefe, F (1999) Chronic pain-associated behaviors in the nursing home: resident versus caregiver perceptions. Pain 80:577-88
Keefe, F J; Caldwell, D S; Baucom, D et al. (1999) Spouse-assisted coping skills training in the management of knee pain in osteoarthritis: long-term followup results. Arthritis Care Res 12:101-11
Keefe, F J; Bonk, V (1999) Psychosocial assessment of pain in patients having rheumatic diseases. Rheum Dis Clin North Am 25:81-103
Weiner, D K; Peterson, B L; Logue, P et al. (1998) Predictors of pain self-report in nursing home residents. Aging (Milano) 10:411-20

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