Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
2R01AR039157-08
Application #
2079421
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1993-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Northwestern University at Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611

  Publications

Zhang, Li; Bertucci, Anne M; Ramsey-Goldman, Rosalind et al. (2009) Regulatory T cell (Treg) subsets return in patients with refractory lupus following stem cell transplantation, and TGF-beta-producing CD8+ Treg cells are associated with immunological remission of lupus. J Immunol 183:6346-58
Kaliyaperumal, Arunan; Michaels, Marissa A; Datta, Syamal K (2002) Naturally processed chromatin peptides reveal a major autoepitope that primes pathogenic T and B cells of lupus. J Immunol 168:2530-7
Babu, John Sam; Sun, Tiedan; Xu, Luting et al. (2002) B cell stimulatory effects of alpha-enolase that is differentially expressed in NZB mouse B cells. Clin Immunol 104:293-304
Yi, Y; McNerney, M; Datta, S K (2000) Regulatory defects in Cbl and mitogen-activated protein kinase (extracellular signal-related kinase) pathways cause persistent hyperexpression of CD40 ligand in human lupus T cells. J Immunol 165:6627-34
Lu, L; Kaliyaperumal, A; Boumpas, D T et al. (1999) Major peptide autoepitopes for nucleosome-specific T cells of human lupus. J Clin Invest 104:345-55
Kaliyaperumal, A; Michaels, M A; Datta, S K (1999) Antigen-specific therapy of murine lupus nephritis using nucleosomal peptides: tolerance spreading impairs pathogenic function of autoimmune T and B cells. J Immunol 162:5775-83
Kalled, S L; Cutler, A H; Datta, S K et al. (1998) Anti-CD40 ligand antibody treatment of SNF1 mice with established nephritis: preservation of kidney function. J Immunol 160:2158-65
Shi, Y; Kaliyaperumal, A; Lu, L et al. (1998) Promiscuous presentation and recognition of nucleosomal autoepitopes in lupus: role of autoimmune T cell receptor alpha chain. J Exp Med 187:367-78
Datta, S K (1998) Production of pathogenic antibodies: cognate interactions between autoimmune T and B cells. Lupus 7:591-6
Datta, S K; Kaliyaperumal, A; Mohan, C et al. (1997) T helper cells driving pathogenic anti-DNA autoantibody production in lupus: nucleosomal epitopes and CD40 ligand signals. Lupus 6:333-6

Showing the most recent 10 out of 22 publications