Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR040124-04
Application #
3160410
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1989-08-05
Project End
1992-07-31
Budget Start
1992-07-01
Budget End
1992-07-31
Support Year
4
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Washington University
Department
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Dayan, S; Stashenko, P; Niederman, R et al. (2004) Oral epithelial overexpression of IL-1alpha causes periodontal disease. J Dent Res 83:786-90
Robert, C; Klein, C; Cheng, G et al. (2003) Gene therapy to target dendritic cells from blood to lymph nodes. Gene Ther 10:1479-86
Murphy, Jo-Ellen; Morales, Romeo E; Scott, Jordan et al. (2003) IL-1 alpha, innate immunity, and skin carcinogenesis: the effect of constitutive expression of IL-1 alpha in epidermis on chemical carcinogenesis. J Immunol 170:5697-703
Armerding, D; Fuhlbrigge, R C; Kieffer, J D et al. (2001) Tonsillar B cells do not express PSGL-1, but a significant fraction displays the cutaneous lymphocyte antigen and exhibits effective E- and P-selectin ligand activity. Int Arch Allergy Immunol 126:78-90
Armerding, D; Kupper, T S (1999) Functional cutaneous lymphocyte antigen can be induced in essentially all peripheral blood T lymphocytes. Int Arch Allergy Immunol 119:212-22
Lee, R T; Briggs, W H; Cheng, G C et al. (1997) Mechanical deformation promotes secretion of IL-1 alpha and IL-1 receptor antagonist. J Immunol 159:5084-8
Williams, I R; Ort, R J; Daley, D et al. (1996) Constitutive expression of B7-1 (CD80) on mouse keratinocytes does not prevent development of chemically induced skin papillomas and carcinomas. J Immunol 156:3382-8
Groves, R W; Rauschmayr, T; Nakamura, K et al. (1996) Inflammatory and hyperproliferative skin disease in mice that express elevated levels of the IL-1 receptor (type I) on epidermal keratinocytes. Evidence that IL-1-inducible secondary cytokines produced by keratinocytes in vivo can cause skin disease. J Clin Invest 98:336-44
Groves, R W; Mizutani, H; Kieffer, J D et al. (1995) Inflammatory skin disease in transgenic mice that express high levels of interleukin 1 alpha in basal epidermis. Proc Natl Acad Sci U S A 92:11874-8
Groves, R W; Giri, J; Sims, J et al. (1995) Inducible expression of type 2 IL-1 receptors by cultured human keratinocytes. Implications for IL-1-mediated processes in epidermis. J Immunol 154:4065-72

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