Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
2R01AR040908-05
Application #
2080334
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1992-02-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Pathology
Type
Schools of Medicine
DUNS #
201373169
City
New York
State
NY
Country
United States
Zip Code
10065
Zan, Hong; Zhang, Jinsong; Al-Qahtani, Ahmed et al. (2011) Endonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regions. Mol Immunol 48:610-22
Xu, Zhenming; Fulop, Zsolt; Wu, Guikai et al. (2010) 14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination. Nat Struct Mol Biol 17:1124-35
Zan, Hong; Casali, Paolo (2008) AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID. Mol Immunol 46:45-61
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Komori, Atsumasa; Xu, Zhenming; Wu, Xiaoping et al. (2006) Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEmu enhancer and 3'Ealpha enhancers in human lymphoblastoid B cells. Mol Immunol 43:1817-26

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