Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR041412-05
Application #
2080675
Study Section
Special Emphasis Panel (ZRG4-OBM-2 (06))
Project Start
1991-09-30
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Barnes-Jewish Hospital
Department
Type
DUNS #
City
Saint Louis
State
MO
Country
United States
Zip Code
63110

  Publications

Alvarez, Jessica A; Ziegler, Thomas R; Millson, Erin C et al. (2016) Body composition and lung function in cystic fibrosis and their association with adiposity and normal-weight obesity. Nutrition 32:447-52
Gao, Yuhao; Qian, Wei-Ping; Dark, Kimberly et al. (2004) Estrogen prevents bone loss through transforming growth factor beta signaling in T cells. Proc Natl Acad Sci U S A 101:16618-23
Cenci, Simone; Toraldo, Gianluca; Weitzmann, M Neale et al. (2003) Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator. Proc Natl Acad Sci U S A 100:10405-10
Toraldo, Gianluca; Roggia, Cristiana; Qian, Wei-Ping et al. (2003) IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor kappa B ligand and tumor necrosis factor alpha from T cells. Proc Natl Acad Sci U S A 100:125-30
Weitzmann, M Neale; Roggia, Cristiana; Toraldo, Gianluca et al. (2002) Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency. J Clin Invest 110:1643-50
Srivastava, S; Toraldo, G; Weitzmann, M N et al. (2001) Estrogen decreases osteoclast formation by down-regulating receptor activator of NF-kappa B ligand (RANKL)-induced JNK activation. J Biol Chem 276:8836-40
Roggia, C; Gao, Y; Cenci, S et al. (2001) Up-regulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo. Proc Natl Acad Sci U S A 98:13960-5
Cenci, S; Weitzmann, M N; Roggia, C et al. (2000) Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha. J Clin Invest 106:1229-37
Cenci, S; Weitzmann, M N; Gentile, M A et al. (2000) M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss. J Clin Invest 105:1279-87
Srivastava, S; Weitzmann, M N; Cenci, S et al. (1999) Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD. J Clin Invest 104:503-13

Showing the most recent 10 out of 21 publications