Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
3R01AR041653-04A2S1
Application #
2521540
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1992-07-16
Project End
2000-06-30
Budget Start
1997-04-21
Budget End
1997-06-30
Support Year
4
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Physiology
Type
Schools of Medicine
DUNS #
660735098
City
Worcester
State
MA
Country
United States
Zip Code
01655
Ni, Shaowei; Hong, Feng; Brewer, Paul D et al. (2009) Kinetic and motor functions mediated by distinct regions of the regulatory light chain of smooth muscle myosin. Biochim Biophys Acta 1794:1599-605
Sugimoto, Yasunobu; Sato, Osamu; Watanabe, Shinya et al. (2009) Reverse conformational changes of the light chain-binding domain of myosin V and VI processive motor heads during and after hydrolysis of ATP by small-angle X-ray solution scattering. J Mol Biol 392:420-35
Watanabe, Shinya; Umeki, Nobuhisa; Ikebe, Reiko et al. (2008) Impacts of Usher syndrome type IB mutations on human myosin VIIa motor function. Biochemistry 47:9505-13
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Li, Xiang-Dong; Jung, Hyun Suk; Wang, Qizhi et al. (2008) The globular tail domain puts on the brake to stop the ATPase cycle of myosin Va. Proc Natl Acad Sci U S A 105:1140-5
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Takizawa, Norio; Ikebe, Reiko; Ikebe, Mitsuo et al. (2007) Supervillin slows cell spreading by facilitating myosin II activation at the cell periphery. J Cell Sci 120:3792-803
Komatsu, Satoshi; Ikebe, Mitsuo (2007) The phosphorylation of myosin II at the Ser1 and Ser2 is critical for normal platelet-derived growth factor induced reorganization of myosin filaments. Mol Biol Cell 18:5081-90
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