Abstract

This research is designed to determine the extent to which variations in cognitive behavior therapy reduce disease activity and improve the mental health of older adults with rheumatoid arthritis (RA). The study combines field assessments, laboratory tests of stress reactivity and clinical evaluations of the mental and physical health of subjects in a longitudinal design. After pre-testing, 210 RA patients will be randomly selected in one of three treatments: Cognitive-Behavior Therapy for Pain (CBT-P), Cognitive-Behavior Therapy for Depression (CBT-D) or Education Group only (EG), which serves as a control. The distinction between pain and depression as foci of CBT in RA is supported by previously funded research by the investigator on interpersonal stress and disease activity in persons with arthritis. Illness severity, depressive symptoms and interpersonal difficulties are expected to predict psychological and physiologic stress responses in participants. Stress reactivity measures are expected to predict the course of illness over time. Those receiving CBT-D are expected to show the greatest improvement in physical functioning, mental health and disease activity. Successful treatment is expected to alter stress responses, leading to better physical and mental health over time.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR041687-09
Application #
6799757
Study Section
Special Emphasis Panel (ZRG1-RPHB-3 (01))
Program Officer
Ader, Deborah N
Project Start
1994-04-10
Project End
2007-05-31
Budget Start
2004-06-01
Budget End
2007-05-31
Support Year
9
Fiscal Year
2004
Total Cost
$396,676
Indirect Cost

  Institution

Name
Arizona State University-Tempe Campus
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
943360412
City
Tempe
State
AZ
Country
United States
Zip Code
85287

  Publications

Mun, Chung Jung; Thummala, Kirti; Davis, Mary C et al. (2017) Predictors and social consequences of daily pain expectancy among adults with chronic pain. Pain 158:1224-1233
Zautra, Alex J; Sturgeon, John A (2016) Examining the complexities of affective experience will enhance our understanding of pain and inform new interventions designed to bolster resilience. Pain 157:1586-7
Carlesso, L C; Sturgeon, J A; Zautra, A J (2016) Exploring the relationship between disease-related pain and cortisol levels in women with osteoarthritis. Osteoarthritis Cartilage 24:2048-2054
Davis, Mary C; Zautra, Alex J; Wolf, Laurie D et al. (2015) Mindfulness and cognitive-behavioral interventions for chronic pain: differential effects on daily pain reactivity and stress reactivity. J Consult Clin Psychol 83:24-35
Sturgeon, John A; Yeung, Ellen WanHeung; Zautra, Alex J (2014) Respiratory sinus arrhythmia: a marker of resilience to pain induction. Int J Behav Med 21:961-5
Sturgeon, John A; Zautra, Alex J (2013) State and trait pain catastrophizing and emotional health in rheumatoid arthritis. Ann Behav Med 45:69-77
Davis, Mary C; Okun, Morris A; Kruszewski, Denise et al. (2010) Sex differences in the relations of positive and negative daily events and fatigue in adults with rheumatoid arthritis. J Pain 11:1338-47
Finan, Patrick H; Hessler, Eric E; Amazeen, Polemnia G et al. (2010) Oscillations in daily pain prediction accuracy. Nonlinear Dynamics Psychol Life Sci 14:27-46
Finan, P H; Okun, M A; Kruszewski, D et al. (2010) Interplay of concurrent positive and negative interpersonal events in the prediction of daily negative affect and fatigue for rheumatoid arthritis patients. Health Psychol 29:429-37
Smith, Bruce W; Zautra, Alex J (2008) The effects of anxiety and depression on weekly pain in women with arthritis. Pain 138:354-61

Showing the most recent 10 out of 19 publications