Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR041880-03
Application #
2081058
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1994-03-15
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
New York University
Department
Dermatology
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
De Filippo, Elisabetta; Schiedel, Anke C; Manga, Prashiela (2017) Interaction between G Protein-Coupled Receptor 143 and Tyrosinase: Implications for Understanding Ocular Albinism Type 1. J Invest Dermatol 137:457-465
De Filippo, Elisabetta; Manga, Prashiela; Schiedel, Anke C (2017) Identification of Novel G Protein-Coupled Receptor 143 Ligands as Pharmacologic Tools for Investigating X-Linked Ocular Albinism. Invest Ophthalmol Vis Sci 58:3118-3126
Arowojolu, Omotayo A; Orlow, Seth J; Elbuluk, Nada et al. (2017) The nuclear factor (erythroid-derived 2)-like 2 (NRF2) antioxidant response promotes melanocyte viability and reduces toxicity of the vitiligo-inducing phenol monobenzone. Exp Dermatol 26:637-644
Manga, Prashiela; Elbuluk, Nada; Orlow, Seth J (2016) Recent advances in understanding vitiligo. F1000Res 5:
Murase, Daiki; Hachiya, Akira; Fullenkamp, Rachel et al. (2016) Variation in Hsp70-1A Expression Contributes to Skin Color Diversity. J Invest Dermatol 136:1681-1691
Doudican, Nicole A; Wen, Shih Ya; Mazumder, Amitabha et al. (2014) Identification of agents that promote endoplasmic reticulum stress using an assay that monitors luciferase secretion. J Biomol Screen 19:575-84
Cheng, Tsing; Orlow, Seth J; Manga, Prashiela (2013) Loss of Oca2 disrupts the unfolded protein response and increases resistance to endoplasmic reticulum stress in melanocytes. Pigment Cell Melanoma Res 26:826-34
Wang, Claire Q F; Akalu, Yemsratch T; Suarez-Farinas, Mayte et al. (2013) IL-17 and TNF synergistically modulate cytokine expression while suppressing melanogenesis: potential relevance to psoriasis. J Invest Dermatol 133:2741-2752
Toosi, Siavash; Orlow, Seth J; Manga, Prashiela (2012) Vitiligo-inducing phenols activate the unfolded protein response in melanocytes resulting in upregulation of IL6 and IL8. J Invest Dermatol 132:2601-9
Manga, Prashiela; Orlow, Seth J (2011) Informed reasoning: repositioning of nitisinone to treat oculocutaneous albinism. J Clin Invest 121:3828-31

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