Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR041916-03
Application #
2081098
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1994-06-01
Project End
1997-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Pennsylvania
Department
Orthopedics
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Lindborg, Carter M; Brennan, Tracy A; Wang, Haitao et al. (2018) Cartilage-derived retinoic acid-sensitive protein (CD-RAP): A stage-specific biomarker of heterotopic endochondral ossification (HEO) in fibrodysplasia ossificans progressiva (FOP). Bone 109:153-157
Amalfitano, Matthew; Fyfe, Billie; Thomas, Sumi V et al. (2018) A case report of mesenteric heterotopic ossification: Histopathologic and genetic findings. Bone 109:56-60
Al Mukaddam, Mona; Rajapakse, Chamith S; Pignolo, Robert J et al. (2018) Imaging assessment of fibrodysplasia ossificans progressiva: Qualitative, quantitative and questionable. Bone 109:147-152
Brennan, Tracy A; Lindborg, Carter M; Bergbauer, Christian R et al. (2018) Mast cell inhibition as a therapeutic approach in fibrodysplasia ossificans progressiva (FOP). Bone 109:259-266
Haupt, Julia; Xu, Meiqi; Shore, Eileen M (2018) Variable signaling activity by FOP ACVR1 mutations. Bone 109:232-240
Rajapakse, Chamith S; Lindborg, Carter; Wang, Haitao et al. (2017) Analog Method for Radiographic Assessment of Heterotopic Bone in Fibrodysplasia Ossificans Progressiva. Acad Radiol 24:321-327
Kaplan, Frederick S; Pignolo, Robert J; Al Mukaddam, Mona M et al. (2017) Hard targets for a second skeleton: therapeutic horizons for fibrodysplasia ossificans progressiva (FOP). Expert Opin Orphan Drugs 5:291-294
Pacifici, Maurizio; Shore, Eileen M (2016) Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders. Cytokine Growth Factor Rev 27:93-104
Wang, Haitao; Lindborg, Carter; Lounev, Vitali et al. (2016) Cellular Hypoxia Promotes Heterotopic Ossification by Amplifying BMP Signaling. J Bone Miner Res 31:1652-65
Chakkalakal, Salin A; Uchibe, Kenta; Convente, Michael R et al. (2016) Palovarotene Inhibits Heterotopic Ossification and Maintains Limb Mobility and Growth in Mice With the Human ACVR1(R206H) Fibrodysplasia Ossificans Progressiva (FOP) Mutation. J Bone Miner Res 31:1666-75

Showing the most recent 10 out of 91 publications