Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR042047-02
Application #
2081249
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1995-06-15
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Jacob, Justin T; Coulombe, Pierre A; Kwan, Raymond et al. (2018) Types I and II Keratin Intermediate Filaments. Cold Spring Harb Perspect Biol 10:
Coulombe, Pierre A (2017) The Molecular Revolution in Cutaneous Biology: Keratin Genes and their Associated Disease: Diversity, Opportunities, and Challenges. J Invest Dermatol 137:e67-e71
Coulombe, Pierre A (2016) Discovery of keratin function and role in genetic diseases: the year that 1991 was. Mol Biol Cell 27:2807-10
Wang, Fengrong; Zieman, Abigail; Coulombe, Pierre A (2016) Skin Keratins. Methods Enzymol 568:303-50
Feng, Xia; Coulombe, Pierre A (2015) Complementary roles of specific cysteines in keratin 14 toward the assembly, organization, and dynamics of intermediate filaments in skin keratinocytes. J Biol Chem 290:22507-19
Feng, Xia; Coulombe, Pierre A (2015) A role for disulfide bonding in keratin intermediate filament organization and dynamics in skin keratinocytes. J Cell Biol 209:59-72
van Steensel, Maurice A M; Coulombe, Pierre A; Kaspar, Roger L et al. (2014) Report of the 10th Annual International Pachyonychia Congenita Consortium Meeting. J Invest Dermatol 134:588-591
Alvarado, David M; Coulombe, Pierre A (2014) Directed expression of a chimeric type II keratin partially rescues keratin 5-null mice. J Biol Chem 289:19435-47
Chung, Byung-Min; Rotty, Jeremy D; Coulombe, Pierre A (2013) Networking galore: intermediate filaments and cell migration. Curr Opin Cell Biol 25:600-12
Pan, Xiaoou; Hobbs, Ryan P; Coulombe, Pierre A (2013) The expanding significance of keratin intermediate filaments in normal and diseased epithelia. Curr Opin Cell Biol 25:47-56

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