Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
3R01AR043520-02S1
Application #
2327403
Study Section
Special Emphasis Panel (SRC (75))
Project Start
1996-07-01
Project End
1997-08-31
Budget Start
1996-07-01
Budget End
1996-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Vermont & St Agric College
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405
Collins, Cheryl C; Bashant, Kathleen; Erikson, Cuixia et al. (2016) Necroptosis of Dendritic Cells Promotes Activation of ?? T Cells. J Innate Immun 8:479-92
Divan, Ali; Budd, Ralph C; Tobin, Richard P et al. (2015) ?? T Cells and dendritic cells in refractory Lyme arthritis. J Leukoc Biol 97:653-63
Saligrama, P T; Fortner, K A; Secinaro, M A et al. (2014) IL-15 maintains T-cell survival via S-nitrosylation-mediated inhibition of caspase-3. Cell Death Differ 21:904-14
Koenig, Andreas; Fortner, Karen A; King, Benjamin R et al. (2012) Proliferating ?? T cells manifest high and spatially confined caspase-3 activity. Immunology 135:276-86
Shi, Cuixia; Sahay, Bikash; Russell, Jennifer Q et al. (2011) Reduced immune response to Borrelia burgdorferi in the absence of ?? T cells. Infect Immun 79:3940-6
Thai, Phan T; Collins, Cheryl C; Fortner, Karen A et al. (2011) Increased caspase activity primes human Lyme arthritis synovial ?? T cells for proliferation and death. Hum Immunol 72:1168-75
Collins, Cheryl; Shi, Cuixia; Russell, Jennifer Q et al. (2008) Activation of gamma delta T cells by Borrelia burgdorferi is indirect via a TLR- and caspase-dependent pathway. J Immunol 181:2392-8
Koenig, A; Russell, J Q; Rodgers, W A et al. (2008) Spatial differences in active caspase-8 defines its role in T-cell activation versus cell death. Cell Death Differ 15:1701-11
Misra, Ravi S; Russell, Jennifer Q; Koenig, Andreas et al. (2007) Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation. J Biol Chem 282:19365-74
Shi, Cuixia; Wolfe, Julie; Russell, Jennifer Q et al. (2006) Fas ligand deficiency impairs host inflammatory response against infection with the spirochete Borrelia burgdorferi. Infect Immun 74:1156-60

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