Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR046249-05
Application #
6511986
Study Section
Pathobiochemistry Study Section (PBC)
Program Officer
Tyree, Bernadette
Project Start
1999-07-15
Project End
2004-06-30
Budget Start
2002-07-01
Budget End
2003-06-30
Support Year
5
Fiscal Year
2002
Total Cost
$212,146
Indirect Cost
Name
Cleveland Clinic Lerner
Department
Other Basic Sciences
Type
Schools of Medicine
DUNS #
135781701
City
Cleveland
State
OH
Country
United States
Zip Code
44195
Bhattaram, Pallavi; Muschler, George; Wixler, Viktor et al. (2018) Inflammatory Cytokines Stabilize SOXC Transcription Factors to Mediate the Transformation of Fibroblast-Like Synoviocytes in Arthritic Disease. Arthritis Rheumatol 70:371-382
Liu, Chia-Feng; Angelozzi, Marco; Haseeb, Abdul et al. (2018) SOX9 is dispensable for the initiation of epigenetic remodeling and the activation of marker genes at the onset of chondrogenesis. Development 145:
Ferguson, James; Devarajan, Mahima; DiNuoscio, Gregg et al. (2018) PRC2 Is Dispensable in Vivo for ?-Catenin-Mediated Repression of Chondrogenesis in the Mouse Embryonic Cranial Mesenchyme. G3 (Bethesda) 8:491-503
Kuwajima, Takaaki; Soares, Célia A; Sitko, Austen A et al. (2017) SoxC Transcription Factors Promote Contralateral Retinal Ganglion Cell Differentiation and Axon Guidance in the Mouse Visual System. Neuron 93:1110-1125.e5
Lefebvre, Véronique; Dvir-Ginzberg, Mona (2017) SOX9 and the many facets of its regulation in the chondrocyte lineage. Connect Tissue Res 58:2-14
Liu, Chia-Feng; Samsa, William E; Zhou, Guang et al. (2017) Transcriptional control of chondrocyte specification and differentiation. Semin Cell Dev Biol 62:34-49
Lefebvre, Véronique; Bhattaram, Pallavi (2016) SOXC Genes and the Control of Skeletogenesis. Curr Osteoporos Rep 14:32-8
Liu, Chia-Feng; Lefebvre, Véronique (2015) The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis. Nucleic Acids Res 43:8183-203
Huang, Alice H; Riordan, Timothy J; Pryce, Brian et al. (2015) Musculoskeletal integration at the wrist underlies the modular development of limb tendons. Development 142:2431-41
Lefebvre, Véronique; Bhattaram, Pallavi (2015) Prg4-expressing cells: articular stem cells or differentiated progeny in the articular chondrocyte lineage? Arthritis Rheumatol 67:1151-4

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