Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
7R01AR048816-03
Application #
6905953
Study Section
Special Emphasis Panel (ZRG1-SMB (01))
Program Officer
Nuckolls, Glen H
Project Start
2002-12-01
Project End
2007-11-30
Budget Start
2004-04-01
Budget End
2004-11-30
Support Year
3
Fiscal Year
2004
Total Cost
$307,301
Indirect Cost
Name
Northshore University Healthsystem Research Institute
Department
Type
DUNS #
154538107
City
Evanston
State
IL
Country
United States
Zip Code
60201
Fox, Michael D; Carson, Vincent J; Feng, Han-Zhong et al. (2018) TNNT1 nemaline myopathy: natural history and therapeutic frontier. Hum Mol Genet 27:3272-3282
Xu, Zherong; Feng, Xin; Dong, Juan et al. (2017) Cardiac troponin T and fast skeletal muscle denervation in ageing. J Cachexia Sarcopenia Muscle 8:808-823
Jin, Jian-Ping (2016) Evolution, Regulation, and Function of N-terminal Variable Region of Troponin T: Modulation of Muscle Contractility and Beyond. Int Rev Cell Mol Biol 321:1-28
Feng, Han-Zhong; Chen, Xuequn; Malek, Moh H et al. (2016) Slow recovery of the impaired fatigue resistance in postunloading mouse soleus muscle corresponding to decreased mitochondrial function and a compensatory increase in type I slow fibers. Am J Physiol Cell Physiol 310:C27-40
Wei, Bin; Jin, J-P (2016) TNNT1, TNNT2, and TNNT3: Isoform genes, regulation, and structure-function relationships. Gene 582:1-13
Gunther, Laura K; Feng, Han-Zhong; Wei, Hongguang et al. (2016) Effect of N-Terminal Extension of Cardiac Troponin I on the Ca(2+) Regulation of ATP Binding and ADP Dissociation of Myosin II in Native Cardiac Myofibrils. Biochemistry 55:1887-97
Sheng, Juan-Juan; Jin, Jian-Ping (2016) TNNI1, TNNI2 and TNNI3: Evolution, regulation, and protein structure-function relationships. Gene 576:385-94
Amarasinghe, Chinthaka; Hossain, M Moazzem; Jin, J-P (2016) Functional Basis of Three New Recessive Mutations of Slow Skeletal Muscle Troponin T Found in Non-Amish TNNT1 Nemaline Myopathies. Biochemistry 55:4560-7
Liu, Rong; Jin, J-P (2016) Calponin isoforms CNN1, CNN2 and CNN3: Regulators for actin cytoskeleton functions in smooth muscle and non-muscle cells. Gene 585:143-153
Mondal, Anupom; Jin, J-P (2016) Protein Structure-Function Relationship at Work: Learning from Myopathy Mutations of the Slow Skeletal Muscle Isoform of Troponin T. Front Physiol 7:449

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