Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA005945-21S1
Application #
3163213
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1978-12-01
Project End
1988-08-31
Budget Start
1985-09-15
Budget End
1986-08-31
Support Year
21
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Institute for Cancer Research
Department
Type
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19111
Khan, S H; Sorof, S (1994) Liver fatty acid-binding protein: specific mediator of the mitogenesis induced by two classes of carcinogenic peroxisome proliferators. Proc Natl Acad Sci U S A 91:848-52
Sorof, S (1994) Modulation of mitogenesis by liver fatty acid binding protein. Cancer Metastasis Rev 13:317-36
Keler, T; Sorof, S (1993) Growth promotion of transfected hepatoma cells by liver fatty acid binding protein. J Cell Physiol 157:33-40
Keler, T; Barker, C S; Sorof, S (1992) Specific growth stimulation by linoleic acid in hepatoma cell lines transfected with the target protein of a liver carcinogen. Proc Natl Acad Sci U S A 89:4830-4
Khan, S H; Sorof, S (1990) Preferential binding of growth inhibitory prostaglandins by the target protein of a carcinogen. Proc Natl Acad Sci U S A 87:9401-5
Raza, H; Pongubala, J R; Sorof, S (1989) Specific high affinity binding of lipoxygenase metabolites of arachidonic acid by liver fatty acid binding protein. Biochem Biophys Res Commun 161:448-55
Munir, K M; Custer, R P; Sorof, S (1989) Normal hepatocytes exhibiting histone H3 with antibody accessible sites that are cryptic in carcinogen-altered hepatocytes. Cancer Res 49:424-32
Munir, K M; Blackburn, G R; Sorof, S (1988) Late target protein of the carcinogen N-2-fluorenylacetamide in rat liver. Cancer Res 48:6745-52
Bassuk, J A; Tsichlis, P N; Sorof, S (1987) Liver fatty acid binding protein is the mitosis-associated polypeptide target of a carcinogen in rat hepatocytes. Proc Natl Acad Sci U S A 84:7547-51
Sorof, S; Custer, R P (1987) Elevated expression and cell cycle deregulation of a mitosis-associated target polypeptide of a carcinogen in hyperplastic and malignant rat hepatocytes. Cancer Res 47:210-20

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