Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA010941-26
Application #
2085926
Study Section
Special Emphasis Panel (ZRG2-ET-2 (03))
Project Start
1977-09-01
Project End
2000-02-29
Budget Start
1996-05-15
Budget End
1997-02-28
Support Year
26
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Jiang, Shuxian; Alberich-Jorda, Meritxell; Zagozdzon, Radoslaw et al. (2011) Cannabinoid receptor 2 and its agonists mediate hematopoiesis and hematopoietic stem and progenitor cell mobilization. Blood 117:827-38
Parmar, Kalindi; Mauch, Peter; Vergilio, Jo-Anne et al. (2007) Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia. Proc Natl Acad Sci U S A 104:5431-6
Parmar, Kalindi; Burdick, Daniel; Ethier, Matthew et al. (2005) Murine side population cells contain cobblestone area-forming cell activity in mobilized blood. Stem Cells Dev 14:452-61
Parmar, Kalindi; Sauk-Schubert, Calies; Burdick, Daniel et al. (2003) Sca+CD34- murine side population cells are highly enriched for primitive stem cells. Exp Hematol 31:244-50
van Os, R; Sheridan, T M; Robinson, S et al. (2001) Immunogenicity of Ly5 (CD45)-antigens hampers long-term engraftment following minimal conditioning in a murine bone marrow transplantation model. Stem Cells 19:80-7
Robinson, S N; Freedman, A S; Neuberg, D S et al. (2000) Loss of marrow reserve from dose-intensified chemotherapy results in impaired hematopoietic reconstitution after autologous transplantation: CD34(+), CD34(+)38(-), and week-6 CAFC assays predict poor engraftment. Exp Hematol 28:1325-33
van Os, R; Robinson, S; Sheridan, T et al. (2000) Granulocyte-colony stimulating factor impedes recovery from damage caused by cytotoxic agents through increased differentiation at the expense of self-renewal. Stem Cells 18:120-7
van Os, R; Robinson, S N; Drukteinis, D et al. (2000) Respiratory burst of neutrophils is not required for stem cell mobilization in mice. Br J Haematol 111:695-9
van Os, R; Avraham, H; Banu, N et al. (1999) Recombinant adeno-associated virus-based vectors provide short-term rather than long-term transduction of primitive hematopoietic stem cells. Stem Cells 17:117-20
van Os, R; Robinson, S; Sheridan, T et al. (1998) Granulocyte colony-stimulating factor enhances bone marrow stem cell damage caused by repeated administration of cytotoxic agents. Blood 92:1950-6

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