Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA018282-21
Application #
2086699
Study Section
Virology Study Section (VR)
Project Start
1978-12-01
Project End
2001-06-30
Budget Start
1996-09-15
Budget End
1997-06-30
Support Year
21
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
075524595
City
Seattle
State
WA
Country
United States
Zip Code
98109
Matsen 4th, Frederick A; Small, Christopher T; Soliven, Khanh et al. (2014) A novel Bayesian method for detection of APOBEC3-mediated hypermutation and its application to zoonotic transmission of simian foamy viruses. PLoS Comput Biol 10:e1003493
Stenbak, Carolyn R; Craig, Karen L; Ivanov, Sergei B et al. (2014) New World simian foamy virus infections in vivo and in vitro. J Virol 88:982-91
Feeroz, Mostafa M; Soliven, Khanh; Small, Christopher T et al. (2013) Population dynamics of rhesus macaques and associated foamy virus in Bangladesh. Emerg Microbes Infect 2:e29
Lee, Eun-Gyung; Stenbak, Carolyn R; Linial, Maxine L (2013) Foamy virus assembly with emphasis on pol encapsidation. Viruses 5:886-900
Jackson, Dana L; Lee, Eun-Gyung; Linial, Maxine L (2013) Expression of prototype foamy virus pol as a Gag-Pol fusion protein does not change the timing of reverse transcription. J Virol 87:1252-4
Soliven, Khanh; Wang, Xiaoxing; Small, Christopher T et al. (2013) Simian foamy virus infection of rhesus macaques in Bangladesh: relationship of latent proviruses and transcriptionally active viruses. J Virol 87:13628-39
Lee, Eun-Gyung; Sinicrope, Amber; Jackson, Dana L et al. (2012) Foamy virus Pol protein expressed as a Gag-Pol fusion retains enzymatic activities, allowing for infectious virus production. J Virol 86:5992-6001
Yu, Shuyuarn F; Lujan, Phillip; Jackson, Dana L et al. (2011) The DEAD-box RNA helicase DDX6 is required for efficient encapsidation of a retroviral genome. PLoS Pathog 7:e1002303
Lee, Eun-Gyung; Roy, Jacqueline; Jackson, Dana et al. (2011) Foamy retrovirus integrase contains a Pol dimerization domain required for protease activation. J Virol 85:1655-61
Lee, Eun-Gyung; Kuppers, Daniel; Horn, Megan et al. (2008) A premature termination codon mutation at the C terminus of foamy virus Gag downregulates the levels of spliced pol mRNA. J Virol 82:1656-64

Showing the most recent 10 out of 56 publications