Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA018689-20
Application #
2086719
Study Section
Molecular Biology Study Section (MBY)
Project Start
1976-06-30
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
20
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02215
Adams, Kenneth W; Kletsov, Sergey; Lamm, Ryan J et al. (2017) Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells. PLoS One 12:e0170076
Nayak, G; Cooper, G M (2012) p53 is a major component of the transcriptional and apoptotic program regulated by PI 3-kinase/Akt/GSK3 signaling. Cell Death Dis 3:e400
Terragni, Jolyon; Nayak, Gauri; Banerjee, Swati et al. (2011) The E-box binding factors Max/Mnt, MITF, and USF1 act coordinately with FoxO to regulate expression of proapoptotic and cell cycle control genes by phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3 signaling. J Biol Chem 286:36215-27
Tullai, John W; Graham, Julie R; Cooper, Geoffrey M (2011) A GSK-3-mediated transcriptional network maintains repression of immediate early genes in quiescent cells. Cell Cycle 10:3072-7
Tullai, John W; Tacheva, Silvia; Owens, Laura J et al. (2011) AP-1 is a component of the transcriptional network regulated by GSK-3 in quiescent cells. PLoS One 6:e20150
Mullenbrock, Steven; Shah, Janki; Cooper, Geoffrey M (2011) Global expression analysis identified a preferentially nerve growth factor-induced transcriptional program regulated by sustained mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) and AP-1 protein activation during PC12 cell dif J Biol Chem 286:45131-45
Graham, Julie R; Tullai, John W; Cooper, Geoffrey M (2010) GSK-3 represses growth factor-inducible genes by inhibiting NF-kappaB in quiescent cells. J Biol Chem 285:4472-80
Graham, Julie R; Hendershott, Melissa C; Terragni, Jolyon et al. (2010) mRNA degradation plays a significant role in the program of gene expression regulated by phosphatidylinositol 3-kinase signaling. Mol Cell Biol 30:5295-305
Saxena, Utsav H; Owens, Laura; Graham, Julie R et al. (2010) Prolyl isomerase Pin1 regulates transcription factor LSF (TFCP2) by facilitating dephosphorylation at two serine-proline motifs. J Biol Chem 285:31139-47
Saxena, Utsav H; Powell, Christina M H; Fecko, Jill K et al. (2009) Phosphorylation by cyclin C/cyclin-dependent kinase 2 following mitogenic stimulation of murine fibroblasts inhibits transcriptional activity of LSF during G1 progression. Mol Cell Biol 29:2335-45

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