Synthetic procedures will be developed to introduce functional groups in simple and complex molecules. The chemistry, in particular cycloadditions, of small ring heterocycles will be investigated. Methods of synthesis and new heterocyclic systems will be developed and their chemistry studied. The stereochemistry, conformational analysis and mechanisms of these reactions will be investigated. Stereochemistry of reactions in four-membered ring and their ring expansion will be studied. Some of these compounds are of interest as potential anticancer agents.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA019203-11
Application #
3165113
Study Section
(SSS)
Project Start
1979-06-01
Project End
1986-11-30
Budget Start
1985-06-01
Budget End
1986-11-30
Support Year
11
Fiscal Year
1985
Total Cost
Indirect Cost
Name
State University of NY, Binghamton
Department
Type
Schools of Arts and Sciences
DUNS #
090189965
City
Binghamton
State
NY
Country
United States
Zip Code
13902