Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA019492-20
Application #
2086775
Study Section
Biochemistry Study Section (BIO)
Project Start
1976-06-30
Project End
1997-02-28
Budget Start
1995-03-01
Budget End
1997-02-28
Support Year
20
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Biochemistry
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Yang, B; Gathy, K N; Coleman, M S (1995) T-cell specific avian TdT: characterization of the cDNA and recombinant enzyme. Nucleic Acids Res 23:2041-8
Bhaumik, D; Yang, B; Trangas, T et al. (1994) Identification of a tripartite basal promoter which regulates human terminal deoxynucleotidyl transferase gene expression. J Biol Chem 269:15861-7
Sorscher, D H; Yang, B; Bhaumik, D et al. (1994) Initiation of transcription at the human terminal deoxynucleotidyl transferase gene promoter: a novel role for the TATA binding protein. Biochemistry 33:11025-32
Coleman, M S; Yang, B; Sorscher, D (1992) Regulation of terminal deoxynucleotidyl transferase gene expression in mice and men. Crit Rev Eukaryot Gene Expr 2:237-50
Farrar, Y J; Evans, R K; Beach, C M et al. (1991) Interactions of photoactive DNAs with terminal deoxynucleotidyl transferase: identification of peptides in the DNA binding domain. Biochemistry 30:3075-82
Medin, J A; Hunt, L; Gathy, K et al. (1990) Efficient, low-cost protein factories: expression of human adenosine deaminase in baculovirus-infected insect larvae. Proc Natl Acad Sci U S A 87:2760-4
Trangas, T; Coleman, M S (1989) Tissue-specific expression of human terminal deoxynucleotidyl transferase is regulated at the transcriptional level. Biochem Biophys Res Commun 164:750-7
Evans, R K; Beach, C M; Coleman, M S (1989) Photoaffinity labeling of terminal deoxynucleotidyl transferase. 2. Identification of peptides in the nucleotide binding domain. Biochemistry 28:713-20
Riley, L K; Morrow, J K; Danton, M J et al. (1988) Human terminal deoxyribonucleotidyltransferase: molecular cloning and structural analysis of the gene and 5' flanking region. Proc Natl Acad Sci U S A 85:2489-93
Robbins, D J; Coleman, M S (1988) Initiator role of double stranded DNA in terminal transferase catalyzed polymerization reactions. Nucleic Acids Res 16:2943-57

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