Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA021141-18
Application #
2086926
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1979-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
18
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Pennsylvania State University
Department
Pathology
Type
Schools of Medicine
DUNS #
129348186
City
Hershey
State
PA
Country
United States
Zip Code
17033
Crone, T M; Schalles, S L; Benedict, C M et al. (1999) Growth inhibition by a triple ribozyme targeted to repetitive B2 transcripts. Hepatology 29:1114-23
Weisz, J; Clawson, G A; Creveling, C R (1998) Biogenesis and inactivation of catecholestrogens. Adv Pharmacol 42:828-33
Weisz, J; Fritz-Wolz, G; Clawson, G A et al. (1998) Induction of nuclear catechol-O-methyltransferase by estrogens in hamster kidney: implications for estrogen-induced renal cancer. Carcinogenesis 19:1307-12
Benedict, C M; Pan, W; Loy, S E et al. (1998) Triple ribozyme-mediated down-regulation of the retinoblastoma gene. Carcinogenesis 19:1223-30
Clawson, G A; Benedict, C M; Kelley, M R et al. (1997) Focal nuclear hepatocyte response to oxidative damage following low dose thioacetamide intoxication. Carcinogenesis 18:1663-8
Ren, L; Clawson, G A (1997) Studies on rLMP7, a beta-subunit of the multicatalytic proteinase. Exp Cell Res 234:105-14
Clawson, G A (1996) Protease inhibitors and carcinogenesis: a review. Cancer Invest 14:597-608
Benedict, C M; Clawson, G A (1996) Nuclear multicatalytic proteinase subunit RRC3 is important for growth regulation in hepatocytes. Biochemistry 35:11612-21
Clawson, G A; Schalles, S L; Wolz, G et al. (1996) Focal altered compartmentation of repetitive B2 (Alu-like) sequences in rat liver following hepatocarcinogen exposure. Cell Growth Differ 7:635-46
Clawson, G A; Ren, L; Isom, H C (1995) Nuclear scaffold-associated protease: in situ nuclear localization and effects of a protease inhibitor on growth and morphology of a ras-transformed hepatocyte cell line. Hepatology 22:1230-5

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