Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA022294-13S1
Application #
3165801
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1990-02-12
Project End
1993-07-31
Budget Start
1990-08-01
Budget End
1991-07-31
Support Year
13
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Emory University
Department
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Yue, K T; Taylor, K L; Kinkade Jr, J M et al. (1997) X-ray absorption and resonance raman spectroscopy of human myeloperoxidase at neutral and acid pH. Biochim Biophys Acta 1338:282-94
Taylor, K L; Strobel, F; Yue, K T et al. (1995) Isolation and identification of a protoheme IX derivative released during autolytic cleavage of human myeloperoxidase. Arch Biochem Biophys 316:635-42
Uhlinger, D J; Taylor, K L; Lambeth, J D (1994) p67-phox enhances the binding of p47-phox to the human neutrophil respiratory burst oxidase complex. J Biol Chem 269:22095-8
Pinnix, I B; Guzman, G S; Bonkovsky, H L et al. (1994) The post-translational processing of myeloperoxidase is regulated by the availability of heme. Arch Biochem Biophys 312:447-58
Ballinger, C A; Mendis-Handagama, C; Kalmar, J R et al. (1994) Changes in the localization of catalase during differentiation of neutrophilic granulocytes. Blood 83:2654-68
Gilbert, C S; Parmley, R T; Rice, W G et al. (1993) Heterogeneity of peroxidase-positive granules in normal human an Chediak-Higashi neutrophils. J Histochem Cytochem 41:837-49
Taylor, K L; Pohl, J; Kinkade Jr, J M (1992) Unique autolytic cleavage of human myeloperoxidase. Implications for the involvement of active site MET409. J Biol Chem 267:25282-8
Taylor, K L; Uhlinger, D J; Kinkade Jr, J M (1992) Expression of recombinant myeloperoxidase using a baculovirus expression system. Biochem Biophys Res Commun 187:1572-8
Castaneda, V L; Parmley, R T; Pinnix, I B et al. (1992) Ultrastructural, immunochemical, and cytochemical study of myeloperoxidase in myeloid leukemia HL-60 cells following treatment with succinylacetone, an inhibitor of heme biosynthesis. Exp Hematol 20:916-24
Pereira, H A; Spitznagel, J K; Winton, E F et al. (1990) The ontogeny of a 57-Kd cationic antimicrobial protein of human polymorphonuclear leukocytes: localization to a novel granule population. Blood 76:825-34

Showing the most recent 10 out of 28 publications