Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA026376-17
Application #
2087501
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1979-07-01
Project End
2000-12-31
Budget Start
1996-02-15
Budget End
1996-12-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Health Science Center San Antonio
Department
Biochemistry
Type
Schools of Medicine
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Vent, Julia; Wyatt, Todd A; Smith, D David et al. (2005) Direct involvement of the isotype-specific C-terminus of beta tubulin in ciliary beating. J Cell Sci 118:4333-41
Dumontet, Charles; Isaac, Sylvie; Souquet, Pierre-Jean et al. (2005) Expression of class III beta tubulin in non-small cell lung cancer is correlated with resistance to taxane chemotherapy. Bull Cancer 92:E25-30
Gupta, Suvroma; Banerjee, Mithu; Poddar, Asim et al. (2005) Biphasic kinetics of the colchicine-tubulin interaction: role of amino acids surrounding the A ring of bound colchicine molecule. Biochemistry 44:10181-8
Yeh, I-Tien; Luduena, Richard F (2004) The betaII isotype of tubulin is present in the cell nuclei of a variety of cancers. Cell Motil Cytoskeleton 57:96-106
Walss-Bass, Consuelo; Kreisberg, Jeffrey I; Luduena, Richard F (2003) Effect of the antitumor drug vinblastine on nuclear betaII-tubulin in cultured rat kidney mesangial cells. Invest New Drugs 21:15-20
Jensen-Smith, Heather C; Eley, Jonquille; Steyger, Peter S et al. (2003) Cell type-specific reduction of beta tubulin isotypes synthesized in the developing gerbil organ of Corti. J Neurocytol 32:185-97
Perry, Brian; Jensen-Smith, Heather C; Luduena, Richard F et al. (2003) Selective expression of beta tubulin isotypes in gerbil vestibular sensory epithelia and neurons. J Assoc Res Otolaryngol 4:329-38
Jensen-Smith, Heather C; Luduena, Richard F; Hallworth, Richard (2003) Requirement for the betaI and betaIV tubulin isotypes in mammalian cilia. Cell Motil Cytoskeleton 55:213-20
Khan, Israr A; Luduena, Richard F (2003) Different effects of vinblastine on the polymerization of isotypically purified tubulins from bovine brain. Invest New Drugs 21:3-13
Xu, Keliang; Luduena, Richard F (2002) Characterization of nuclear betaII-tubulin in tumor cells: a possible novel target for taxol. Cell Motil Cytoskeleton 53:39-52

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