Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA027706-16
Application #
2087633
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1980-04-01
Project End
1999-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Roswell Park Cancer Institute Corp
Department
Type
DUNS #
City
Buffalo
State
NY
Country
United States
Zip Code
14263
Dong, Yan; Ganther, Howard E; Stewart, Carleton et al. (2002) Identification of molecular targets associated with selenium-induced growth inhibition in human breast cells using cDNA microarrays. Cancer Res 62:708-14
Dong, Yan; Ip, Clement; Ganther, Howard (2002) Evidence of a field effect associated with mammary cancer chemoprevention by methylseleninic acid. Anticancer Res 22:27-32
Ip, C; Dong, Y (2001) Methylselenocysteine modulates proliferation and apoptosis biomarkers in premalignant lesions of the rat mammary gland. Anticancer Res 21:863-7
Dong, Y; Lisk, D; Block, E et al. (2001) Characterization of the biological activity of gamma-glutamyl-Se-methylselenocysteine: a novel, naturally occurring anticancer agent from garlic. Cancer Res 61:2923-8
Ip, C; Birringer, M; Block, E et al. (2000) Chemical speciation influences comparative activity of selenium-enriched garlic and yeast in mammary cancer prevention. J Agric Food Chem 48:2062-70
Ip, C; Thompson, H J; Ganther, H E (2000) Selenium modulation of cell proliferation and cell cycle biomarkers in normal and premalignant cells of the rat mammary gland. Cancer Epidemiol Biomarkers Prev 9:49-54
Ip, C; Zhu, Z; Thompson, H J et al. (1999) Chemoprevention of mammary cancer with Se-allylselenocysteine and other selenoamino acids in the rat. Anticancer Res 19:2875-80
Ip, C (1998) Lessons from basic research in selenium and cancer prevention. J Nutr 128:1845-54
Ip, C; Lisk, D J (1997) Modulation of phase I and phase II xenobiotic-metabolizing enzymes by selenium-enriched garlic in rats. Nutr Cancer 28:184-8
Ip, C; Lisk, D J; Thompson, H J (1996) Selenium-enriched garlic inhibits the early stage but not the late stage of mammary carcinogenesis. Carcinogenesis 17:1979-82

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