Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA028936-16
Application #
2087839
Study Section
Immunobiology Study Section (IMB)
Project Start
1981-01-01
Project End
2001-02-08
Budget Start
1996-05-01
Budget End
1997-02-28
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Duke University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Hudson, Lori L; Louise Markert, M; Devlin, Blythe H et al. (2007) Human T cell reconstitution in DiGeorge syndrome and HIV-1 infection. Semin Immunol 19:297-309
Sempowski, Gregory D; Gooding, Maria E; Liao, H X et al. (2002) T cell receptor excision circle assessment of thymopoiesis in aging mice. Mol Immunol 38:841-8
Sempowski, Gregory D; Rhein, Maria E; Scearce, Richard M et al. (2002) Leukemia inhibitory factor is a mediator of Escherichia coli lipopolysaccharide-induced acute thymic atrophy. Eur J Immunol 32:3066-70
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Haynes, B F; Markert, M L; Sempowski, G D et al. (2000) The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infection. Annu Rev Immunol 18:529-60
Liao, H X; Montefiori, D C; Patel, D D et al. (2000) Linkage of the CCR5 Delta 32 mutation with a functional polymorphism of CD45RA. J Immunol 165:148-57
Sempowski, G D; Hale, L P; Sundy, J S et al. (2000) Leukemia inhibitory factor, oncostatin M, IL-6, and stem cell factor mRNA expression in human thymus increases with age and is associated with thymic atrophy. J Immunol 164:2180-7
Haynes, B F (1999) HIV infection and the dynamic interplay between the thymus and the peripheral T cell pool. Clin Immunol 92:3-5
Flores, K G; Li, J; Sempowski, G D et al. (1999) Analysis of the human thymic perivascular space during aging. J Clin Invest 104:1031-9

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