Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA029995-15
Application #
2087996
Study Section
Pathology B Study Section (PTHB)
Project Start
1981-05-01
Project End
1999-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Pathology
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
De Larco, J E; Wuertz, B R; Rosner, K A et al. (2001) A potential role for interleukin-8 in the metastatic phenotype of breast carcinoma cells. Am J Pathol 158:639-46
De Larco, J E; Wuertz, B R; Manivel, J C et al. (2001) Progression and enhancement of metastatic potential after exposure of tumor cells to chemotherapeutic agents. Cancer Res 61:2857-61
Simpson, M A; Reiland, J; Burger, S R et al. (2001) Hyaluronan synthase elevation in metastatic prostate carcinoma cells correlates with hyaluronan surface retention, a prerequisite for rapid adhesion to bone marrow endothelial cells. J Biol Chem 276:17949-57
Reiland, J; Furcht, L T; McCarthy, J B (1999) CXC-chemokines stimulate invasion and chemotaxis in prostate carcinoma cells through the CXCR2 receptor. Prostate 41:78-88
Li, C; McCarthy, J B; Furcht, L T et al. (1997) An all-D amino acid peptide model of alpha1(IV)531-543 from type IV collagen binds the alpha3beta1 integrin and mediates tumor cell adhesion, spreading, and motility. Biochemistry 36:15404-10
Braunewell, K H; Pesheva, P; McCarthy, J B et al. (1995) Functional involvement of sciatic nerve-derived versican- and decorin-like molecules and other chondroitin sulphate proteoglycans in ECM-mediated cell adhesion and neurite outgrowth. Eur J Neurosci 7:805-14
Streuli, C H; Schmidhauser, C; Bailey, N et al. (1995) Laminin mediates tissue-specific gene expression in mammary epithelia. J Cell Biol 129:591-603
Furcht, L T; Skubitz, A P; Fields, G B (1994) Tumor cell invasion, matrix metalloproteinases, and the dogma. Lab Invest 70:781-3
Pesheva, P; Probstmeier, R; Skubitz, A P et al. (1994) Tenascin-R (J1 160/180 inhibits fibronectin-mediated cell adhesion--functional relatedness to tenascin-C. J Cell Sci 107 ( Pt 8):2323-33
Mooradian, D L; McCarthy, J B; Komanduri, K V et al. (1992) Effects of transforming growth factor-beta 1 on human pulmonary adenocarcinoma cell adhesion, motility, and invasion in vitro. J Natl Cancer Inst 84:523-7

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