Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
7R01CA030103-16
Application #
2007337
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1987-04-15
Project End
2000-02-29
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Mo, Yin-Yuan; Yu, Yanni; Theodosiou, Elena et al. (2005) A role for Ubc9 in tumorigenesis. Oncogene 24:2677-83
Kamalakaran, Sitharthan; Radhakrishnan, Senthil K; Beck, William T (2005) Identification of estrogen-responsive genes using a genome-wide analysis of promoter elements for transcription factor binding sites. J Biol Chem 280:21491-7
Mo, Yin-Yuan; Yu, Yanni; Ee, P L Rachel et al. (2004) Overexpression of a dominant-negative mutant Ubc9 is associated with increased sensitivity to anticancer drugs. Cancer Res 64:2793-8
Ee, P L Rachel; He, Xiaolong; Ross, Douglas D et al. (2004) Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference. Mol Cancer Ther 3:1577-83
Ee, Pui Lai Rachel; Kamalakaran, Sitharthan; Tonetti, Debra et al. (2004) Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene. Cancer Res 64:1247-51
He, Xiaolong; Ee, P L Rachel; Coon, John S et al. (2004) Alternative splicing of the multidrug resistance protein 1/ATP binding cassette transporter subfamily gene in ovarian cancer creates functional splice variants and is associated with increased expression of the splicing factors PTB and SRp20. Clin Cancer Res 10:4652-60
Mo, Yin-Yuan; Yu, Yanni; Shen, Zhiyuan et al. (2002) Nucleolar delocalization of human topoisomerase I in response to topotecan correlates with sumoylation of the protein. J Biol Chem 277:2958-64
Cai, L; Lim, K; Ren, S et al. (2001) Synthesis and in vitro antitumor activity of oligonucleotide-tethered and related platinum complexes. J Med Chem 44:2959-65
Morgan, S E; Beck, W T (2001) Role of an inverted CCAAT element in human topoisomerase IIalpha gene expression in ICRF-187-sensitive and -resistant CEM leukemic cells. Mol Pharmacol 59:203-11
Mo, Y Y; Wang, P; Beck, W T (2000) Functional expression of human DNA topoisomerase I and its subcellular localization in HeLa cells. Exp Cell Res 256:480-90

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