Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA030490-16
Application #
2088075
Study Section
Virology Study Section (VR)
Project Start
1981-07-01
Project End
1999-12-31
Budget Start
1996-04-01
Budget End
1996-12-31
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Berkeley
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
094878337
City
Berkeley
State
CA
Country
United States
Zip Code
94704
Bleichert, Franziska; Leitner, Alexander; Aebersold, Ruedi et al. (2018) Conformational control and DNA-binding mechanism of the metazoan origin recognition complex. Proc Natl Acad Sci U S A 115:E5906-E5915
Bleichert, Franziska; Botchan, Michael R; Berger, James M (2017) Mechanisms for initiating cellular DNA replication. Science 355:
Nodelman, Ilana M; Bleichert, Franziska; Patel, Ashok et al. (2017) Interdomain Communication of the Chd1 Chromatin Remodeler across the DNA Gyres of the Nucleosome. Mol Cell 65:447-459.e6
Parker, Matthew W; Botchan, Michael R; Berger, James M (2017) Mechanisms and regulation of DNA replication initiation in eukaryotes. Crit Rev Biochem Mol Biol 52:107-144
Costa, Alessandro; Ilves, Ivar; Tamberg, Nele et al. (2011) The structural basis for MCM2-7 helicase activation by GINS and Cdc45. Nat Struct Mol Biol 18:471-7
Georlette, Daphne; Ahn, Soyeon; MacAlpine, David M et al. (2007) Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb MuvB/dREAM complex in proliferating cells. Genes Dev 21:2880-96
Beall, Eileen L; Lewis, Peter W; Bell, Maren et al. (2007) Discovery of tMAC: a Drosophila testis-specific meiotic arrest complex paralogous to Myb-Muv B. Genes Dev 21:904-19
Clarey, Megan G; Erzberger, Jan P; Grob, Patricia et al. (2006) Nucleotide-dependent conformational changes in the DnaA-like core of the origin recognition complex. Nat Struct Mol Biol 13:684-90
Remus, Dirk; Beall, Eileen L; Botchan, Michael R (2004) DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding. EMBO J 23:897-907
Beall, Eileen L; Bell, Maren; Georlette, Daphne et al. (2004) Dm-myb mutant lethality in Drosophila is dependent upon mip130: positive and negative regulation of DNA replication. Genes Dev 18:1667-80

Showing the most recent 10 out of 51 publications