Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA031922-14
Application #
2088263
Study Section
Biochemistry Study Section (BIO)
Project Start
1981-09-01
Project End
1997-03-31
Budget Start
1995-04-01
Budget End
1997-03-31
Support Year
14
Fiscal Year
1995
Total Cost
Indirect Cost
Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105
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Bunting, K D; Galipeau, J; Topham, D et al. (1999) Effects of retroviral-mediated MDR1 expression on hematopoietic stem cell self-renewal and differentiation in culture. Ann N Y Acad Sci 872:125-40;discussion 140-1
Bunting, K D; Flynn, K J; Riberdy, J M et al. (1999) Virus-specific immunity after gene therapy in a murine model of severe combined immunodeficiency. Proc Natl Acad Sci U S A 96:232-7
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Allay, J A; Persons, D A; Galipeau, J et al. (1998) In vivo selection of retrovirally transduced hematopoietic stem cells. Nat Med 4:1136-43
Allay, J A; Spencer, H T; Wilkinson, S L et al. (1997) Sensitization of hematopoietic stem and progenitor cells to trimetrexate using nucleoside transport inhibitors. Blood 90:3546-54
Cody, V; Galitsky, N; Luft, J R et al. (1997) Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523. Biochemistry 36:13897-903
Patel, M; Sleep, S E; Lewis, W S et al. (1997) Comparison of the protection of cells from antifolates by transduced human dihydrofolate reductase mutants. Hum Gene Ther 8:2069-77

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