Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA032369-05S3
Application #
3170319
Study Section
(EH)
Project Start
1982-05-01
Project End
1987-11-30
Budget Start
1986-05-01
Budget End
1987-11-30
Support Year
5
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Suny Downstate Medical Center
Department
Type
Schools of Medicine
DUNS #
068552207
City
Brooklyn
State
NY
Country
United States
Zip Code
11203
Sadasivan, E; Cedeno, M M; Rothenberg, S P (1994) Characterization of the gene encoding a folate-binding protein expressed in human placenta. Identification of promoter activity in a G-rich SP1 site linked with the tandemly repeated GGAAG motif for the ets encoded GA-binding protein. J Biol Chem 269:4725-35
Luhrs, C A; Raskin, C A; Durbin, R et al. (1992) Transfection of a glycosylated phosphatidylinositol-anchored folate-binding protein complementary DNA provides cells with the ability to survive in low folate medium. J Clin Invest 90:840-7
Sadasivan, E; Cedeno, M; Rothenberg, S P (1992) Genomic organization of the gene and a related pseudogene for a human folate binding protein. Biochim Biophys Acta 1131:91-4
Luhrs, C A (1991) The role of glycosylation in the biosynthesis and acquisition of ligand-binding activity of the folate-binding protein in cultured KB cells. Blood 77:1171-80
Sadasivan, E; Rothenberg, S P (1989) The complete amino acid sequence of a human folate binding protein from KB cells determined from the cDNA. J Biol Chem 264:5806-11
Luhrs, C A; Slomiany, B L (1989) A human membrane-associated folate binding protein is anchored by a glycosyl-phosphatidylinositol tail. J Biol Chem 264:21446-9
da Costa, M; Rothenberg, S P (1988) Characterization of the folate-binding proteins associated with the plasma membrane of rat liver. Biochim Biophys Acta 939:533-41
Sadasivan, E; da Costa, M; Rothenberg, S P et al. (1987) Purification, properties, and immunological characterization of folate-binding proteins from human leukemia cells. Biochim Biophys Acta 925:36-47
Luhrs, C A; Pitiranggon, P; da Costa, M et al. (1987) Purified membrane and soluble folate binding proteins from cultured KB cells have similar amino acid compositions and molecular weights but differ in fatty acid acylation. Proc Natl Acad Sci U S A 84:6546-9
Luhrs, C A; Sadasivan, E; da Costa, M et al. (1986) The isolation and properties of multiple forms of folate binding protein in cultured KB cells. Arch Biochem Biophys 250:94-105