Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA037585-13
Application #
2089398
Study Section
Special Emphasis Panel (ZRG3-ET-2 (02))
Project Start
1984-07-01
Project End
1999-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Kansas State University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Manhattan
State
KS
Country
United States
Zip Code
66506
Ding, G Y; Shen, T; Center, M S (1999) Multidrug resistance-associated protein (MRP) mediated transport of daunomycin and leukotriene C4 (LTC4) in isolated plasma membrane vesicles. Anticancer Res 19:3243-8
Zhu, Q; Sun, H; Center, M S (1997) Functional analysis of the nucleotide binding domains of the multidrug resistance protein (MRP). Oncol Res 9:229-36
Sun, H; Zhu, Q; Center, M S (1996) Expression and characterization of the multidrug resistance-associated protein in insect cells infected with a recombinant baculovirus. Oncol Res 8:287-93
Zhu, Q; Center, M S (1996) Evidence that SP1 modulates transcriptional activity of the multidrug resistance-associated protein gene. DNA Cell Biol 15:105-11
Ma, L; Krishnamachary, N; Center, M S (1995) Phosphorylation of the multidrug resistance associated protein gene encoded protein P190. Biochemistry 34:3338-43
Jedlitschky, G; Leier, I; Buchholz, U et al. (1994) ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein. Cancer Res 54:4833-6
Zhu, Q; Center, M S (1994) Cloning and sequence analysis of the promoter region of the MRP gene of HL60 cells isolated for resistance to adriamycin. Cancer Res 54:4488-92
Krishnamachary, N; Ma, L; Zheng, L et al. (1994) Analysis of MRP gene expression and function in HL60 cells isolated for resistance to adriamycin. Oncol Res 6:119-27
Barrand, M A; Rhodes, T; Center, M S et al. (1993) Chemosensitisation and drug accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell lung cancer cells expressing a 190k membrane protein distinct from P-glycoprotein. Eur J Cancer 29A:408-15
Center, M S (1993) Non-P-glycoprotein multidrug resistance in cell lines which are defective in the cellular accumulation of drug. Cytotechnology 12:109-25

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