Information about diet, use of alcoholic beverages, and use of tobacco was obtained, together with other information in 1957-58 at the baseline examination of 2,107 middle-aged, employed men participating in the Western Electric Health Study. Participants were re-examined annually through 1969. Interim data on alcohol and tobacco were obtained at each examination, and interim information about diet was obtained in 1959 and 1960. Follow-up for vital status and morbidity from cancer was completed in 1978 with only 3 participants lost to follow-up, and a similar follow-up on the twenty-fifth anniversary of the initial examination is in progress. These data will be used to investigate prospectively the association between dietary variables (e.g., vitamins A and C, animal fat, animal protein, dietary cholesterol), consumption of alcoholic beverages (primarily beer and liquor), use of tobacco, and risk of malignant neoplasms. These data will help to determine whether dietary habits during middle-age affect risk of commonly occurring cancers in men (e.g., lung, colon, rectum, bladder) 10-25 years later -- i.e., over a period of time sufficiently long so it is reasonable to infer that the dietary habits preceded induction of the cancer. The reliability with which men in the seventh and eighth decades of life can recollect and report dietary habits, use of alcohol, and use of tobacco 25 years previously will also be investigated.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA038326-02
Application #
3176401
Study Section
Epidemiology and Disease Control Subcommittee 3 (EDC)
Project Start
1984-04-01
Project End
1987-03-31
Budget Start
1985-04-01
Budget End
1987-03-31
Support Year
2
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Type
Schools of Public Health
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225
Dyer, A R; Stamler, J; Shekelle, R B (1992) Serum cholesterol and mortality from coronary heart disease in young, middle-aged, and older men and women from three Chicago epidemiologic studies. Ann Epidemiol 2:51-7
Goff Jr, D C; Shekelle, R B; Katan, M B et al. (1992) Does body fatness modify the association between dietary cholesterol and risk of coronary death? Results from the Chicago Western Electric Study. Arterioscler Thromb 12:755-61
Almada, S J; Zonderman, A B; Shekelle, R B et al. (1991) Neuroticism and cynicism and risk of death in middle-aged men: the Western Electric Study. Psychosom Med 53:165-75
Crews, D E; Stamler, J; Dyer, A (1991) Conditions other than underlying cause of death listed on death certificates provide additional useful information for epidemiologic research. Epidemiology 2:271-5
Shekelle, R B; Vernon, S W; Ostfeld, A M (1991) Personality and coronary heart disease. Psychosom Med 53:176-84
Shekelle, R B; Rossof, A H; Stamler, J (1991) Dietary cholesterol and incidence of lung cancer: the Western Electric Study. Am J Epidemiol 134:480-4;discussion 543-4
Hamm, P; Shekelle, R B; Stamler, J (1989) Large fluctuations in body weight during young adulthood and twenty-five-year risk of coronary death in men. Am J Epidemiol 129:312-8
Shekelle, R B; Stamler, J (1989) Dietary cholesterol and ischaemic heart disease. Lancet 1:1177-9
Clay, C M; Dyer, A R; Liu, K et al. (1988) Education, smoking and non-cardiovascular mortality: findings in three Chicago epidemiological studies. Int J Epidemiol 17:341-7
LeGrady, D; Dyer, A R; Shekelle, R B et al. (1987) Coffee consumption and mortality in the Chicago Western Electric Company Study. Am J Epidemiol 126:803-12