Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA040358-10
Application #
2090201
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1992-12-01
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
10
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
University of Pennsylvania
Department
Dermatology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Ramirez-Montagut, Teresa; Chow, Andrew; Kochman, Adam A et al. (2007) IFN-gamma and Fas ligand are required for graft-versus-tumor activity against renal cell carcinoma in the absence of lethal graft-versus-host disease. J Immunol 179:1669-80
DiRienzo, Christine G; Murphy, George F; Friedman, Thea M et al. (2007) T-cell receptor V(alpha) usage by effector CD4+Vbeta11+ T cells mediating graft-versus-host disease directed to minor histocompatibility antigens. Biol Blood Marrow Transplant 13:265-76
Zhan, Qian; Signoretti, Sabina; Whitaker-Menezes, Diana et al. (2007) Cytokeratin15-positive basal epithelial cells targeted in graft-versus-host disease express a constitutive antiapoptotic phenotype. J Invest Dermatol 127:106-15
DiRienzo, Christine G; Murphy, George F; Jones, Stephen C et al. (2006) T-cell receptor Valpha spectratype analysis of a CD4-mediated T-cell response against minor histocompatibility antigens involved in severe graft-versus-host disease. Biol Blood Marrow Transplant 12:818-27
Clark, Rachael A; Chong, Benjamin F; Mirchandani, Nina et al. (2006) A novel method for the isolation of skin resident T cells from normal and diseased human skin. J Invest Dermatol 126:1059-70
Durakovic, Nadira; Bezak, Karl B; Skarica, Mario et al. (2006) Host-derived Langerhans cells persist after MHC-matched allografting independent of donor T cells and critically influence the alloresponses mediated by donor lymphocyte infusions. J Immunol 177:4414-25
Sugerman, Philip B; Faber, Sara B; Willis, Lucy M et al. (2004) Kinetics of gene expression in murine cutaneous graft-versus-host disease. Am J Pathol 164:2189-202
Friedman, Thea M; Jones, Stephen C; Statton, Debbie et al. (2004) Evolution of responding CD4+ and CD8+ T-cell repertoires during the development of graft-versus-host disease directed to minor histocompatibility antigens. Biol Blood Marrow Transplant 10:224-35
Choksi, Swati; Kim, Judith C; Whitaker-Menezes, Diana et al. (2004) A CD8 DE loop peptide analog prevents graft-versus-host disease in a multiple minor histocompatibility antigen-mismatched bone marrow transplantation model. Biol Blood Marrow Transplant 10:669-80
Jones, Stephen C; Friedman, Thea M; Murphy, George F et al. (2004) Specific donor Vbeta-associated CD4 T-cell responses correlate with severe acute graft-versus-host disease directed to multiple minor histocompatibility antigens. Biol Blood Marrow Transplant 10:91-105

Showing the most recent 10 out of 77 publications