Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA041451-10
Application #
2090450
Study Section
Experimental Virology Study Section (EVR)
Project Start
1986-08-01
Project End
1998-07-04
Budget Start
1996-02-01
Budget End
1998-07-04
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Eastern Virginia Medical School
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Norfolk
State
VA
Country
United States
Zip Code
23501
Bolin, Lisa L; Hanson, Laura K; Slater, Jacquelyn S et al. (2010) Murine cytomegalovirus US22 protein pM140 protects its binding partner, pM141, from proteasome-dependent but ubiquitin-independent degradation. J Virol 84:2164-8
Hanson, Laura K; Slater, Jacquelyn S; Cavanaugh, Victoria J et al. (2009) Murine cytomegalovirus capsid assembly is dependent on US22 family gene M140 in infected macrophages. J Virol 83:7449-56
Campbell, Ann E; Cavanaugh, Victoria J; Slater, Jacquelyn S (2008) The salivary glands as a privileged site of cytomegalovirus immune evasion and persistence. Med Microbiol Immunol 197:205-13
Cavanaugh, Victoria J; Raulet, David H; Campbell, Ann E (2007) Upregulation of CD94/NKG2A receptors and Qa-1b ligand during murine cytomegalovirus infection of salivary glands. J Gen Virol 88:1440-5
Child, Stephanie J; Hanson, Laura K; Brown, Crystal E et al. (2006) Double-stranded RNA binding by a heterodimeric complex of murine cytomegalovirus m142 and m143 proteins. J Virol 80:10173-80
Karabekian, Zaruhi; Hanson, Laura K; Slater, Jacquelyn S et al. (2005) Complex formation among murine cytomegalovirus US22 proteins encoded by genes M139, M140, and M141. J Virol 79:3525-35
Ciocco-Schmitt, Gina M; Karabekian, Zaruhi; Godfrey, Earl W et al. (2002) Identification and characterization of novel murine cytomegalovirus M112-113 (e1) gene products. Virology 294:199-208
Hanson, L K; Slater, J S; Karabekian, Z et al. (2001) Products of US22 genes M140 and M141 confer efficient replication of murine cytomegalovirus in macrophages and spleen. J Virol 75:6292-302
Hanson, L K; Slater, J S; Karabekian, Z et al. (1999) Replication of murine cytomegalovirus in differentiated macrophages as a determinant of viral pathogenesis. J Virol 73:5970-80
Jones, T R; Hanson, L K; Sun, L et al. (1995) Multiple independent loci within the human cytomegalovirus unique short region down-regulate expression of major histocompatibility complex class I heavy chains. J Virol 69:4830-41