Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA042157-06S1
Application #
3183047
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1986-04-01
Project End
1994-09-30
Budget Start
1991-04-01
Budget End
1991-09-30
Support Year
6
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Type
Organized Research Units
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Miliani de Marval, Paula L; Macias, Everardo; Rounbehler, Robert et al. (2004) Lack of cyclin-dependent kinase 4 inhibits c-myc tumorigenic activities in epithelial tissues. Mol Cell Biol 24:7538-47
Miliani de Marval, Paula L; Macias, Everardo; Conti, Claudio J et al. (2004) Enhanced malignant tumorigenesis in Cdk4 transgenic mice. Oncogene 23:1863-73
Christensen, Laura A; Conti, Claudio J; Fischer, Susan M et al. (2004) Mutation frequencies in murine keratinocytes as a function of carcinogenic status. Mol Carcinog 40:122-33
Gavrielides, M Veronica; Frijhoff, Anita F; Conti, Claudio J et al. (2004) Protein kinase C and prostate carcinogenesis: targeting the cell cycle and apoptotic mechanisms. Curr Drug Targets 5:431-43
Frijhoff, Anita F W; Conti, Claudio J; Senderowicz, Adrian M (2004) Advances in molecular carcinogenesis: current and future use of mouse models to screen and validate molecularly targeted anticancer drugs. Mol Carcinog 39:183-94
Rounbehler, Robert J; Rogers, Pamela M; Conti, Claudio J et al. (2002) Inactivation of E2f1 enhances tumorigenesis in a Myc transgenic model. Cancer Res 62:3276-81
Rodriguez-Puebla, Marcelo L; Miliani de Marval, Paula L; LaCava, Margaret et al. (2002) Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation. Am J Pathol 161:405-11
Russell, Jamie L; Powers, John T; Rounbehler, Robert J et al. (2002) ARF differentially modulates apoptosis induced by E2F1 and Myc. Mol Cell Biol 22:1360-8
Rounbehler, R J; Schneider-Broussard, R; Conti, C J et al. (2001) Myc lacks E2F1's ability to suppress skin carcinogenesis. Oncogene 20:5341-9
Miliani de Marval, P L; Gimenez-Conti, I B; LaCava, M et al. (2001) Transgenic expression of cyclin-dependent kinase 4 results in epidermal hyperplasia, hypertrophy, and severe dermal fibrosis. Am J Pathol 159:369-79

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