|
Lemke, L E; Paine-Murrieta, G D; Taylor, C W et al. (1999) Wortmannin inhibits the growth of mammary tumors despite the existence of a novel wortmannin-insensitive phosphatidylinositol-3-kinase. Cancer Chemother Pharmacol 44:491-7
|
|
Qiao, L; Nan, F; Kunkel, M et al. (1998) 3-Deoxy-D-myo-inositol 1-phosphate, 1-phosphonate, and ether lipid analogues as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell growth. J Med Chem 41:3303-6
|
|
Kirkpatrick, D L; Kuperus, M; Dowdeswell, M et al. (1998) Mechanisms of inhibition of the thioredoxin growth factor system by antitumor 2-imidazolyl disulfides. Biochem Pharmacol 55:987-94
|
|
Powis, G; Gallegos, A; Abraham, R T et al. (1997) Inhibition of intracellular Ca2+ signalling, cytotoxicity and antitumor activity of the herbicide oryzalin and its analogues. Cancer Chemother Pharmacol 41:22-8
|
|
Kunkel, M W; Kirkpatrick, D L; Johnson, J I et al. (1997) Cell line-directed screening assay for inhibitors of thioredoxin reductase signaling as potential anti-cancer drugs. Anticancer Drug Des 12:659-70
|
|
Dvorakova, K; Dorr, R T; Gallegos, A et al. (1997) Pharmacokinetic studies of the herbicide and antitumor compound oryzalin in mice. J Chromatogr B Biomed Sci Appl 696:275-81
|
|
Brunner, G; Zalkow, L; Burgess, E et al. (1996) Inhibition of glycosylphosphatidylinositol (GPI) phospholipase D by suramin-like compounds. Anticancer Res 16:2513-6
|
|
Oblong, J E; Berggren, M; Gasdaska, P Y et al. (1995) Site-directed mutagenesis of Lys36 in human thioredoxin: the highly conserved residue affects reduction rates and growth stimulation but is not essential for the redox protein's biochemical or biological properties. Biochemistry 34:3319-24
|
|
Powis, G; Hill, S R; Frew, T J et al. (1995) Inhibitors of phospholipid intracellular signaling as antiproliferative agents. Med Res Rev 15:121-38
|
|
Powis, G (1994) Recent advances in the development of anticancer drugs that act against signalling pathways. Tumori 80:69-87
|
Showing the most recent 10 out of 53 publications
