Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA042357-16S1
Application #
6796571
Study Section
Experimental Virology Study Section (EVR)
Program Officer
Rosenfeld, Bobby
Project Start
1986-04-01
Project End
2005-04-30
Budget Start
2003-09-05
Budget End
2004-04-30
Support Year
16
Fiscal Year
2003
Total Cost
$29,646
Indirect Cost
Name
New York University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Xi, Qiaoran; Cuesta, Rafael; Schneider, Robert J (2004) Tethering of eIF4G to adenoviral mRNAs by viral 100k protein drives ribosome shunting. Genes Dev 18:1997-2009
Cuesta, Rafael; Xi, Qiaoran; Schneider, Robert J (2004) Structural basis for competitive inhibition of eIF4G-Mnk1 interaction by the adenovirus 100-kilodalton protein. J Virol 78:7707-16
Schneider, Robert J; Mohr, Ian (2003) Translation initiation and viral tricks. Trends Biochem Sci 28:130-6
Cuesta, R; Xi, Q; Schneider, R J (2001) Preferential translation of adenovirus mRNAs in infected cells. Cold Spring Harb Symp Quant Biol 66:259-67
Cuesta, R; Xi, Q; Schneider, R J (2000) Adenovirus-specific translation by displacement of kinase Mnk1 from cap-initiation complex eIF4F. EMBO J 19:3465-74
Yueh, A; Schneider, R J (2000) Translation by ribosome shunting on adenovirus and hsp70 mRNAs facilitated by complementarity to 18S rRNA. Genes Dev 14:414-21
Cuesta, R; Laroia, G; Schneider, R J (2000) Chaperone hsp27 inhibits translation during heat shock by binding eIF4G and facilitating dissociation of cap-initiation complexes. Genes Dev 14:1460-70
Klein, N; Curatola, A M; Schneider, R J (1999) Calcium-induced stabilization of AU-rich short-lived mRNAs is a common default response. Gene Expr 7:357-65
Laroia, G; Cuesta, R; Brewer, G et al. (1999) Control of mRNA decay by heat shock-ubiquitin-proteasome pathway. Science 284:499-502
Feigenblum, D; Walker, R; Schneider, R J (1998) Adenovirus induction of an interferon-regulatory factor during entry into the late phase of infection. J Virol 72:9257-66

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