Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA042664-01
Application #
3184151
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1985-09-15
Project End
1988-08-31
Budget Start
1985-09-15
Budget End
1986-08-31
Support Year
1
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Type
Schools of Medicine
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Sharma, Vivek R; Thomas, Shelia D; Miller, Donald M et al. (2018) Nucleolin Overexpression Confers Increased Sensitivity to the Anti-Nucleolin Aptamer, AS1411. Cancer Invest 36:475-491
Dapic, Virna; Bates, Paula J; Trent, John O et al. (2002) Antiproliferative activity of G-quartet-forming oligonucleotides with backbone and sugar modifications. Biochemistry 41:3676-85
Stewart, Delisha A; Xu, Xiaohua; Thomas, Shelia D et al. (2002) Acridine-modified, clamp-forming antisense oligonucleotides synergize with cisplatin to inhibit c-Myc expression and B16-F0 tumor progression. Nucleic Acids Res 30:2565-74
Bates, Paula J; Reddoch, James F; Hansakul, Pintusorn et al. (2002) Biosensor detection of triplex formation by modified oligonucleotides. Anal Biochem 307:235-43
Stewart, D A; Thomas, S D; Mayfield, C A et al. (2001) Psoralen-modified clamp-forming antisense oligonucleotides reduce cellular c-Myc protein expression and B16-F0 proliferation. Nucleic Acids Res 29:4052-61
Blume, S W; Lebowitz, J; Zacharias, W et al. (1999) The integral divalent cation within the intermolecular purine*purine. pyrimidine structure: a variable determinant of the potential for and characteristics of the triple helical association. Nucleic Acids Res 27:695-702
Kim, H G; Miller, D M (1998) A novel triplex-forming oligonucleotide targeted to human cyclin D1 (bcl-1, proto-oncogene) promoter inhibits transcription in HeLa cells. Biochemistry 37:2666-72
Kim, H G; Reddoch, J F; Mayfield, C et al. (1998) Inhibition of transcription of the human c-myc protooncogene by intermolecular triplex. Biochemistry 37:2299-304
Blume, S W; Guarcello, V; Zacharias, W et al. (1997) Divalent transition metal cations counteract potassium-induced quadruplex assembly of oligo(dG) sequences. Nucleic Acids Res 25:617-25
Ebbinghaus, S W; Vigneswaran, N; Miller, C R et al. (1996) Efficient delivery of triplex forming oligonucleotides to tumor cells by adenovirus-polylysine complexes. Gene Ther 3:287-97

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