Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA042829-01
Application #
3184416
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1986-09-01
Project End
1989-08-31
Budget Start
1986-09-01
Budget End
1987-08-31
Support Year
1
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Tennessee Knoxville
Department
Type
Schools of Veterinary Medicine
DUNS #
City
Knoxville
State
TN
Country
United States
Zip Code
37996
Banerjee, Jheelam; Papu John, Arokya M S; Al-Wadei, Mohammed H et al. (2016) Prevention of pancreatic cancer in a hamster model by cAMP decrease. Oncotarget 7:44430-44441
Al-Wadei, Mohammed H; Banerjee, Jheelam; Al-Wadei, Hussein A N et al. (2016) Nicotine induces self-renewal of pancreatic cancer stem cells via neurotransmitter-driven activation of sonic hedgehog signalling. Eur J Cancer 52:188-96
Banerjee, Jheelam; Al-Wadei, Hussein An; Al-Wadei, Mohammed H et al. (2014) Differential modulation of nicotine-induced gemcitabine resistance by GABA receptor agonists in pancreatic cancer cell xenografts and in vitro. BMC Cancer 14:725
Al-Wadei, Mohammed H; Al-Wadei, Hussein A N; Schuller, Hildegard M (2013) Gamma-amino butyric acid (GABA) prevents the induction of nicotinic receptor-regulated signaling by chronic ethanol in pancreatic cancer cells and normal duct epithelia. Cancer Prev Res (Phila) 6:139-48
Schuller, Hildegard M (2013) Effects of tobacco constituents and psychological stress on the beta-adrenergic regulation of non-small cell lung cancer and pancreatic cancer: implications for intervention. Cancer Biomark 13:133-44
Banerjee, Jheelam; Al-Wadei, Hussein A N; Schuller, Hildegard M (2013) Chronic nicotine inhibits the therapeutic effects of gemcitabine on pancreatic cancer in vitro and in mouse xenografts. Eur J Cancer 49:1152-8
Schuller, Hildegard M; Al-Wadei, Hussein A N (2012) Beta-adrenergic signaling in the development and progression of pulmonary and pancreatic adenocarcinoma. Curr Cancer Ther Rev 8:116-127
Al-Wadei, Mohammed H; Al-Wadei, Hussein A N; Schuller, Hildegard M (2012) Effects of chronic nicotine on the autocrine regulation of pancreatic cancer cells and pancreatic duct epithelial cells by stimulatory and inhibitory neurotransmitters. Carcinogenesis 33:1745-53
Al-Wadei, Mohammed H; Al-Wadei, Hussein A N; Schuller, Hildegard M (2012) Pancreatic cancer cells and normal pancreatic duct epithelial cells express an autocrine catecholamine loop that is activated by nicotinic acetylcholine receptors ýý3, ýý5, and ýý7. Mol Cancer Res 10:239-49
Al-Wadei, Hussein A N; Al-Wadei, Mohammed H; Ullah, Mohammad F et al. (2012) Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer in vitro and in xenograft models of stress-free and stress-exposed mice. PLoS One 7:e43376

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