Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA043540-09
Application #
2091197
Study Section
Pathology B Study Section (PTHB)
Project Start
1987-04-01
Project End
1996-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Walter and Eliza Hall Institute Medical Research
Department
Type
DUNS #
City
Victoria
State
Country
Australia
Zip Code
VIC, -3052
Campbell, Kirsteen J; Vandenberg, Cassandra J; Anstee, Natasha S et al. (2017) Mnt modulates Myc-driven lymphomagenesis. Cell Death Differ 24:2117-2126
Anstee, Natasha S; Vandenberg, Cassandra J; Campbell, Kirsteen J et al. (2017) Overexpression of Mcl-1 exacerbates lymphocyte accumulation and autoimmune kidney disease in lpr mice. Cell Death Differ 24:397-408
Vandenberg, C J; Motoyama, N; Cory, S (2016) FoxO3 suppresses Myc-driven lymphomagenesis. Cell Death Dis 6:e2046
Vandenberg, Cassandra J; Waring, Paul; Strasser, Andreas et al. (2014) Plasmacytomagenesis in E?-v-abl transgenic mice is accelerated when apoptosis is restrained. Blood 124:1099-109
Vandenberg, C J; Josefsson, E C; Campbell, K J et al. (2014) Loss of Bak enhances lymphocytosis but does not ameliorate thrombocytopaenia in BCL-2 transgenic mice. Cell Death Differ 21:676-84
Vandenberg, Cassandra J; Cory, Suzanne (2013) ABT-199, a new Bcl-2-specific BH3 mimetic, has in vivo efficacy against aggressive Myc-driven mouse lymphomas without provoking thrombocytopenia. Blood 121:2285-8
Mason, Kylie D; Lin, Ann; Robb, Lorraine et al. (2013) Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease. Proc Natl Acad Sci U S A 110:2599-604
Happo, Lina; Strasser, Andreas; Cory, Suzanne (2012) BH3-only proteins in apoptosis at a glance. J Cell Sci 125:1081-7
Mérino, D; Strasser, A; Bouillet, P (2012) Bim must be able to engage all pro-survival Bcl-2 family members for efficient tumor suppression. Oncogene 31:3392-6
Gray, Daniel H D; Kupresanin, Fiona; Berzins, Stuart P et al. (2012) The BH3-only proteins Bim and Puma cooperate to impose deletional tolerance of organ-specific antigens. Immunity 37:451-62

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