Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA044059-06S1
Application #
3186595
Study Section
Molecular Biology Study Section (MBY)
Project Start
1986-04-01
Project End
1992-06-30
Budget Start
1991-08-01
Budget End
1992-06-30
Support Year
6
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Cleveland Clinic Lerner
Department
Type
DUNS #
017730458
City
Cleveland
State
OH
Country
United States
Zip Code
44195
Li, Yize; Banerjee, Shuvojit; Goldstein, Stephen A et al. (2017) Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line. Elife 6:
Kindler, Eveline; Gil-Cruz, Cristina; Spanier, Julia et al. (2017) Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. PLoS Pathog 13:e1006195
Birdwell, L Dillon; Zalinger, Zachary B; Li, Yize et al. (2016) Activation of RNase L by Murine Coronavirus in Myeloid Cells Is Dependent on Basal Oas Gene Expression and Independent of Virus-Induced Interferon. J Virol 90:3160-72
Li, Yize; Banerjee, Shuvojit; Wang, Yuyan et al. (2016) Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses. Proc Natl Acad Sci U S A 113:2241-6
Cooper, Daphne A; Banerjee, Shuvojit; Chakrabarti, Arindam et al. (2015) RNase L targets distinct sites in influenza A virus RNAs. J Virol 89:2764-76
Banerjee, Shuvojit; Li, Geqiang; Li, Yize et al. (2015) RNase L is a negative regulator of cell migration. Oncotarget 6:44360-72
Chakrabarti, Arindam; Banerjee, Shuvojit; Franchi, Luigi et al. (2015) RNase L activates the NLRP3 inflammasome during viral infections. Cell Host Microbe 17:466-77
Huang, Hao; Zeqiraj, Elton; Dong, Beihua et al. (2014) Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity. Mol Cell 53:221-34
Silverman, Robert H; Weiss, Susan R (2014) Viral phosphodiesterases that antagonize double-stranded RNA signaling to RNase L by degrading 2-5A. J Interferon Cytokine Res 34:455-63
Banerjee, Shuvojit; Chakrabarti, Arindam; Jha, Babal Kant et al. (2014) Cell-type-specific effects of RNase L on viral induction of beta interferon. MBio 5:e00856-14

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