Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA044800-07
Application #
2091624
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1988-03-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1998-06-30
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Pathology
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Duan, Yu-You; Wu, Jian; Zhu, Jian-Liang et al. (2004) Gene therapy for human alpha1-antitrypsin deficiency in an animal model using SV40-derived vectors. Gastroenterology 127:1222-32
Strayer, D S; Lamothe, M; Wei, D et al. (2001) Generation of recombinant SV40 vectors for gene transfer. Methods Mol Biol 165:103-17
Strayer, D S (2000) Effective gene transfer using viral vectors based on SV40. Methods Mol Biol 133:61-74
Wali, A; Strayer, D S (1999) Comparative effects of virulent and avirulent poxviruses on cell cycle progression. Exp Mol Pathol 66:31-8
Zern, M A; Ozaki, I; Duan, L et al. (1999) A novel SV40-based vector successfully transduces and expresses an alpha 1-antitrypsin ribozyme in a human hepatoma-derived cell line. Gene Ther 6:114-20
Wali, A; Strayer, D S (1999) Infection with vaccinia virus alters regulation of cell cycle progression. DNA Cell Biol 18:837-43
Kondo, R; Feitelson, M A; Strayer, D S (1998) Use of SV40 to immunize against hepatitis B surface antigen: implications for the use of SV40 for gene transduction and its use as an immunizing agent. Gene Ther 5:575-82
Milano Jr, J; Strayer, D S (1998) Effects of overexpression of Ran/TC4 mammalian cells in vitro. Exp Cell Res 239:31-9
Strayer, D S; Kondo, R; Milano, J et al. (1997) Use of SV40-based vectors to transduce foreign genes to normal human peripheral blood mononuclear cells. Gene Ther 4:219-25
Strayer, D S; Duan, L X; Ozaki, I et al. (1997) Titering replication-defective virus for use in gene transfer. Biotechniques 22:447-50

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