Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA044983-10S2
Application #
2446764
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1986-09-01
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
10
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
Ohio State University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210

  Publications

Kim, Jonghan; Hayton, William L; Robinson, John M et al. (2007) Kinetics of FcRn-mediated recycling of IgG and albumin in human: pathophysiology and therapeutic implications using a simplified mechanism-based model. Clin Immunol 122:146-55
Tridandapani, Susheela; Siefker, Kristina; Teillaud, Jean-Luc et al. (2002) Regulated expression and inhibitory function of Fcgamma RIIb in human monocytic cells. J Biol Chem 277:5082-9
Tridandapani, Susheela; Wang, Yijie; Marsh, Clay B et al. (2002) Src homology 2 domain-containing inositol polyphosphate phosphatase regulates NF-kappa B-mediated gene transcription by phagocytic Fc gamma Rs in human myeloid cells. J Immunol 169:4370-8
Lyden, T W; Robinson, J M; Tridandapani, S et al. (2001) The Fc receptor for IgG expressed in the villus endothelium of human placenta is Fc gamma RIIb2. J Immunol 166:3882-9
Tridandapani, S; Lyden, T W; Smith, J L et al. (2000) The adapter protein LAT enhances fcgamma receptor-mediated signal transduction in myeloid cells. J Biol Chem 275:20480-7
Maresco, D L; Osborne, J M; Cooney, D et al. (1999) The SH2-containing 5'-inositol phosphatase (SHIP) is tyrosine phosphorylated after Fc gamma receptor clustering in monocytes. J Immunol 162:6458-65
Maresco, D L; Blue, L E; Culley, L L et al. (1998) Localization of FCGR1 encoding Fcgamma receptor class I in primates: molecular evidence for two pericentric inversions during the evolution of human chromosome 1. Cytogenet Cell Genet 82:71-4
Lowry, M B; Duchemin, A M; Coggeshall, K M et al. (1998) Chimeric receptors composed of phosphoinositide 3-kinase domains and FCgamma receptor ligand-binding domains mediate phagocytosis in COS fibroblasts. J Biol Chem 273:24513-20
Lowry, M B; Duchemin, A M; Robinson, J M et al. (1998) Functional separation of pseudopod extension and particle internalization during Fc gamma receptor-mediated phagocytosis. J Exp Med 187:161-76
Ernst, L K; Duchemin, A M; Miller, K L et al. (1998) Molecular characterization of six variant Fcgamma receptor class I (CD64) transcripts. Mol Immunol 35:943-54

Showing the most recent 10 out of 24 publications