Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA045055-12S1
Application #
2091717
Study Section
Reproductive Biology Study Section (REB)
Project Start
1986-09-30
Project End
1998-01-31
Budget Start
1995-02-01
Budget End
1996-01-31
Support Year
12
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Physiology
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Kazi, Armina A; Jones, Jenny M; Koos, Robert D (2005) Chromatin immunoprecipitation analysis of gene expression in the rat uterus in vivo: estrogen-induced recruitment of both estrogen receptor alpha and hypoxia-inducible factor 1 to the vascular endothelial growth factor promoter. Mol Endocrinol 19:2006-19
Koos, Robert D; Kazi, Armina A; Roberson, Mark S et al. (2005) New insight into the transcriptional regulation of vascular endothelial growth factor expression in the endometrium by estrogen and relaxin. Ann N Y Acad Sci 1041:233-47
Rockwell, L Christie; Pillai, Suresh; Olson, C Erik et al. (2002) Inhibition of vascular endothelial growth factor/vascular permeability factor action blocks estrogen-induced uterine edema and implantation in rodents. Biol Reprod 67:1804-10
Pillai, Suresh B; Jones, Jenny M; Koos, Robert D (2002) Treatment of rats with 17beta-estradiol or relaxin rapidly inhibits uterine estrogen receptor beta1 and beta2 messenger ribonucleic acid levels. Biol Reprod 67:1919-26
Hruska, Kathleen S; Tilli, Maddalena T; Ren, Shuxun et al. (2002) Conditional over-expression of estrogen receptor alpha in a transgenic mouse model. Transgenic Res 11:361-72
Pillai, S B; Rockwell, L C; Sherwood, O D et al. (1999) Relaxin stimulates uterine edema via activation of estrogen receptors: blockade of its effects using ICI 182,780, a specific estrogen receptor antagonist. Endocrinology 140:2426-9
Forsythe, J A; Jiang, B H; Iyer, N V et al. (1996) Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol 16:4604-13
Koos, R D (1995) Increased expression of vascular endothelial growth/permeability factor in the rat ovary following an ovulatory gonadotropin stimulus: potential roles in follicle rupture. Biol Reprod 52:1426-35
Koos, R D; Banks, P K; Inkster, S E et al. (1993) Detection of aromatase and keratinocyte growth factor expression in breast tumors using reverse transcription-polymerase chain reaction. J Steroid Biochem Mol Biol 45:217-25
Cullinan-Bove, K; Koos, R D (1993) Vascular endothelial growth factor/vascular permeability factor expression in the rat uterus: rapid stimulation by estrogen correlates with estrogen-induced increases in uterine capillary permeability and growth. Endocrinology 133:829-37

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