Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA045799-08S1
Application #
2092015
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1987-04-01
Project End
1995-09-28
Budget Start
1994-04-01
Budget End
1995-09-28
Support Year
8
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Johnson, Philip L F; Goronzy, Jörg J; Antia, Rustom (2014) A population biological approach to understanding the maintenance and loss of the T-cell repertoire during aging. Immunology 142:167-75
Scocca, Jane R; Charron, Martin; Shaper, Nancy L et al. (2003) Determination of the half-life of the murine beta4-galactosyltransferase-1 mRNA in somatic cells using the tetracycline-controlled transcriptional regulation system. Biochimie 85:403-7
Lee, J; Sundaram, S; Shaper, N L et al. (2001) Chinese hamster ovary (CHO) cells may express six beta 4-galactosyltransferases (beta 4GalTs). Consequences of the loss of functional beta 4GalT-1, beta 4GalT-6, or both in CHO glycosylation mutants. J Biol Chem 276:13924-34
Joziasse, D H; Shaper, J H; Shaper, N L (1999) The alpha 1,3-galactosyltransferase gene. Subcell Biochem 32:25-48
Snow, D M; Shaper, J H; Shaper, N L et al. (1999) Determination of beta1,4-galactosyltransferase enzymatic activity by capillary electrophoresis and laser-induced fluorescence detection. Anal Biochem 271:36-42
Charron, M; Shaper, N L; Rajput, B et al. (1999) A novel 14-base-pair regulatory element is essential for in vivo expression of murine beta4-galactosyltransferase-I in late pachytene spermatocytes and round spermatids. Mol Cell Biol 19:5823-32
Lo, N W; Shaper, J H; Pevsner, J et al. (1998) The expanding beta 4-galactosyltransferase gene family: messages from the databanks. Glycobiology 8:517-26
Charron, M; Shaper, J H; Shaper, N L (1998) The increased level of beta1,4-galactosyltransferase required for lactose biosynthesis is achieved in part by translational control. Proc Natl Acad Sci U S A 95:14805-10
Johnston, D S; Wright, W W; Shaper, J H et al. (1998) Murine sperm-zona binding, a fucosyl residue is required for a high affinity sperm-binding ligand. A second site on sperm binds a nonfucosylated, beta-galactosyl-capped oligosaccharide. J Biol Chem 273:1888-95
Shaper, N L; Charron, M; Lo, N W et al. (1998) Beta1,4-galactosyltransferase and lactose biosynthesis: recruitment of a housekeeping gene from the nonmammalian vertebrate gene pool for a mammary gland specific function. J Mammary Gland Biol Neoplasia 3:315-24

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