Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA046462-05S1
Application #
2092159
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1990-04-20
Project End
1996-03-31
Budget Start
1994-04-01
Budget End
1996-03-31
Support Year
5
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Biochemistry
Type
Schools of Dentistry
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Brown, Jillian R; Yang, Feng; Sinha, Anjana et al. (2009) Deoxygenated disaccharide analogs as specific inhibitors of beta1-4-galactosyltransferase 1 and selectin-mediated tumor metastasis. J Biol Chem 284:4952-9
Moinpour, Carol M; Donaldson, Gary W; Nakamura, Yoshio (2009) Chemotherapeutic impact on pain and global health-related quality of life in hormone-refractory prostate cancer: Dynamically Modified Outcomes (DYNAMO) analysis of a randomized controlled trial. Qual Life Res 18:147-55
Schuksz, Manuela; Fuster, Mark M; Brown, Jillian R et al. (2008) Surfen, a small molecule antagonist of heparan sulfate. Proc Natl Acad Sci U S A 105:13075-80
Brown, Jillian R; Crawford, Brett E; Esko, Jeffrey D (2007) Glycan antagonists and inhibitors: a fount for drug discovery. Crit Rev Biochem Mol Biol 42:481-515
Moinpour, Carol M; Donaldson, Gary W; Redman, Mary W (2007) Do general dimensions of quality of life add clinical value to symptom data? J Natl Cancer Inst Monogr :31-8
Petrylak, Daniel P; Ankerst, Donna Pauler; Jiang, Caroline S et al. (2006) Evaluation of prostate-specific antigen declines for surrogacy in patients treated on SWOG 99-16. J Natl Cancer Inst 98:516-21
Brown, Jillian R; Fuster, Mark M; Li, Ruixia et al. (2006) A disaccharide-based inhibitor of glycosylation attenuates metastatic tumor cell dissemination. Clin Cancer Res 12:2894-901
Petrylak, Daniel P; Tangen, Catherine M; Hussain, Maha H A et al. (2004) Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med 351:1513-20
Ben-Zaken, Olga; Tzaban, Salit; Tal, Yuval et al. (2003) Cellular heparan sulfate participates in the metabolism of prions. J Biol Chem 278:40041-9
Fuster, Mark M; Brown, Jillian R; Wang, Lianchun et al. (2003) A disaccharide precursor of sialyl Lewis X inhibits metastatic potential of tumor cells. Cancer Res 63:2775-81

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