Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA046465-05S1
Application #
3189738
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1991-09-30
Project End
1995-08-31
Budget Start
1992-09-01
Budget End
1993-08-31
Support Year
5
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Type
Schools of Medicine
DUNS #
622146454
City
Piscataway
State
NJ
Country
United States
Zip Code
08854
Krause, Christopher D; Pestka, Sidney (2007) Historical developments in the research of interferon receptors. Cytokine Growth Factor Rev 18:473-82
Qu, Yongxia; Adler, Victor; Izotova, Lara et al. (2007) The dual-specificity kinases, TOPK and DYRK1A, are critical for oocyte maturation induced by wild-type--but not by oncogenic--ras-p21 protein. Front Biosci 12:5089-97
Krause, Christopher D; Yang, Zhi-Hong; Kim, Young-Sun et al. (2007) Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential. Pharmacol Ther 113:50-87
Pestka, Sidney (2007) The interferons: 50 years after their discovery, there is much more to learn. J Biol Chem 282:20047-51
Qu, Yongxia; Adler, Victor; Chu, Tearina et al. (2006) Two dual specificity kinases are preferentially induced by wild-type rather than by oncogenic RAS-P21 in Xenopus oocytes. Front Biosci 11:2420-7
Krause, Christopher D; He, Wen; Kotenko, Sergei et al. (2006) Modulation of the activation of Stat1 by the interferon-gamma receptor complex. Cell Res 16:113-23
Garcia, Carmen S; Curiel, Rafael E; Mwatibo, James M et al. (2006) The antineoplastic agent bryostatin-1 differentially regulates IFN-gamma receptor subunits in monocytic cells: transcriptional and posttranscriptional control of IFN-gamma R2. J Immunol 177:2707-16
Adler, Victor; Qu, Yongxia; Smith, Steven J et al. (2005) Functional interactions of Raf and MEK with Jun-N-terminal kinase (JNK) result in a positive feedback loop on the oncogenic Ras signaling pathway. Biochemistry 44:10784-95
Krause, Christopher D; Pestka, Sidney (2005) Evolution of the Class 2 cytokines and receptors, and discovery of new friends and relatives. Pharmacol Ther 106:299-346
Pestka, Sidney; Krause, Christopher D; Walter, Mark R (2004) Interferons, interferon-like cytokines, and their receptors. Immunol Rev 202:8-32

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