Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA047044-07
Application #
2092402
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1987-06-01
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Pharmacology
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Yoo, H; Juliano, R L (2000) Enhanced delivery of antisense oligonucleotides with fluorophore-conjugated PAMAM dendrimers. Nucleic Acids Res 28:4225-31
DeLong, R K; Yoo, H; Alahari, S K et al. (1999) Novel cationic amphiphiles as delivery agents for antisense oligonucleotides. Nucleic Acids Res 27:3334-41
Yoo, H; Sazani, P; Juliano, R L (1999) PAMAM dendrimers as delivery agents for antisense oligonucleotides. Pharm Res 16:1799-804
Alahari, S K; DeLong, R; Fisher, M H et al. (1998) Novel chemically modified oligonucleotides provide potent inhibition of P-glycoprotein expression. J Pharmacol Exp Ther 286:419-28
Nolting, A; DeLong, R K; Fisher, M H et al. (1997) Hepatic distribution and clearance of antisense oligonucleotides in the isolated perfused rat liver. Pharm Res 14:516-21
Delong, R; Stephenson, K; Loftus, T et al. (1997) Characterization of complexes of oligonucleotides with polyamidoamine starburst dendrimers and effects on intracellular delivery. J Pharm Sci 86:762-4
Cheng, X; Boyer, J L; Juliano, R L (1997) Selection of peptides that functionally replace a zinc finger in the Sp1 transcription factor by using a yeast combinatorial library. Proc Natl Acad Sci U S A 94:14120-5
Cheng, X; Kay, B K; Juliano, R L (1996) Identification of a biologically significant DNA-binding peptide motif by use of a random phage display library. Gene 171:1-8
Alahari, S K; Dean, N M; Fisher, M H et al. (1996) Inhibition of expression of the multidrug resistance-associated P-glycoprotein of by phosphorothioate and 5' cholesterol-conjugated phosphorothioate antisense oligonucleotides. Mol Pharmacol 50:808-19
Daoud, S S; Forde, N H (1991) Synergistic cytotoxic actions of cisplatin and liposomal valinomycin on human ovarian carcinoma cells. Cancer Chemother Pharmacol 28:370-6

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