Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA048115-07
Application #
2092925
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1988-07-01
Project End
1997-08-31
Budget Start
1996-02-01
Budget End
1997-08-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Yale University
Department
Pathology
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520

  Publications

Thakral, Deepshi; Dobbins, Jessica; Devine, Lesley et al. (2008) Differential expression of the human CD8beta splice variants and regulation of the M-2 isoform by ubiquitination. J Immunol 180:7431-42
Liu, Wenzhong; Mani, Sheida; Davis, Nicole R et al. (2008) Mutation in EGFP domain of LDL receptor-related protein 6 impairs cellular LDL clearance. Circ Res 103:1280-8
Devine, Lesley; Thakral, Deepshi; Nag, Shanta et al. (2006) Mapping the binding site on CD8 beta for MHC class I reveals mutants with enhanced binding. J Immunol 177:3930-8
Attinger, Antoine; Devine, Lesley; Wang-Zhu, Yiran et al. (2005) Molecular basis for the high affinity interaction between the thymic leukemia antigen and the CD8alphaalpha molecule. J Immunol 174:3501-7
Kieffer, Lynda J; Greally, John M; Landres, Inna et al. (2002) Identification of a candidate regulatory region in the human CD8 gene complex by colocalization of DNase I hypersensitive sites and matrix attachment regions which bind SATB1 and GATA-3. J Immunol 168:3915-22
Devine, Lesley; Rogozinski, Linda; Naidenko, Olga V et al. (2002) The complementarity-determining region-like loops of CD8 alpha interact differently with beta 2-microglobulin of the class I molecules H-2Kb and thymic leukemia antigen, while similarly with their alpha 3 domains. J Immunol 168:3881-6
Campbell, N A; Park, M S; Toy, L S et al. (2002) A non-class I MHC intestinal epithelial surface glycoprotein, gp180, binds to CD8. Clin Immunol 102:267-74
Daniels, M A; Devine, L; Miller, J D et al. (2001) CD8 binding to MHC class I molecules is influenced by T cell maturation and glycosylation. Immunity 15:1051-61
Kim, S K; DeMars, R (2001) Epitope clusters in the major outer membrane protein of Chlamydia trachomatis. Curr Opin Immunol 13:429-36
Kim, S K; Devine, L; Angevine, M et al. (2000) Direct detection and magnetic isolation of Chlamydia trachomatis major outer membrane protein-specific CD8+ CTLs with HLA class I tetramers. J Immunol 165:7285-92

Showing the most recent 10 out of 15 publications